Bpsbioscience/CK1ε，GST标签/79349/10μg
商品编号：
79349
品牌：
bpsbioscience
市场价：
¥7800.00
美元价：
4680.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:72kDa
Genbank#:NM_001894
Tag(s):GST-Tag
Background:
CK1εisamemberoftheCK1familyofserine/threonineproteinkinaseswhichplayanimportantroleindiversecellprocesses,includingDNAreplicationandrepair.CK1εisaregulatorofYes-associatedprotein(YAP)transcriptioncoactivatorwhichisakeyregulatoroforgansizeandacandidatehumanoncogene.CK1εisactivatedbyCCK2RandthisthenphosphorylatesPKD2atSer244.PhosphorylationofPKD2leadstoitsnuclearaccumulationandefficientphosphorylationofnuclearPKD2substratesinhumangastriccancercells(1).CKIεcanphosphorylatetopoisomerase(topo)IIalphaatserine-1106andthisregulatestheenzymeactivityandsensitivitytotopoII-targeteddrugs(2).
Description:
FulllengthrecombinanthumanCK1ε,alsoknownasCSNK1E,HCKIE,MGC10398,andCK1E.GenbankAccessionNM_001894N-terminalGST-tag,expressedinSf9cellsviaabaculovirusexpressionsystem.MW=72kDa.
Synonym(s):
CSNK1E,HCKIE,MGC10398,CK1E
Purity:
≥70%
Formulation:
50mMTris-HCL,pH7.5,150mMNaCl,10mMglutathione,0.1mMEDTA,0.25mMDTT,0.1mMPMSF,25%glycerol.
Storage/StABIlity:
Atleast6monthsat–80°C.Avoidfreeze/thawcycles.
Application(s):
Usefulforthekinaseassaykitsandwesternblotting.
Reference(s):
1.vonBlume,J.,etal.,EMBOJ2007;26(22):4619-33.
2.Grozav.AG,etal.,NucleicAcidsRes.2009;37(2):382-92.
ScientificCategory:
Kinase
ProductType:
Protein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
