Bpsbioscience/CDK9/CyclinK，GST标签/40106/10µg
商品编号：
40106
品牌：
bpsbioscience
市场价：
¥7800.00
美元价：
4680.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:68kDa(CDK9),67kDa(CyclinK)
Genbank#:NM_001261,BC015935
Tag(s):N-terminalGST-tag
a.a:fulllength
Background:
CDK9/CyclinKisamemberofthecyclin-dependentproteinkinase(CDK)family.CDK9iscloselyrelatedtocdc28andcdc2andisanimportantregulatorofthecellcycle(1).CDK9isacomponentofthemultiproteincomplexTAK/P-TEFβ.CDK9canmodulateRNApolymeraseII-directedtranscriptionbyphosphorylatingtheC-terminaldomainofthelargestsubunitofRNApolymeraseII.CDK9formsacomplexwithandisregulatedbyitsregulatorysubunitcyclinTorcyclinK.CDK9alsointeractswiththeHIV-1TatproteinwhichsuggestedapossIBLeinvolvementofthisproteininAIDS(2).
Description:
ComplexofrecombinanthumanCDK9andCyclinK,fulllength,withN-terminalGST-tags,(GenBankAccessionNo.NM_001261,andBC015935,respectively)co-expressedinSf9insectcellsviaabaculovirusexpressionsystem.
Synonym(s):
Cyclin-Dependent9,CDK9:CDC2L4,C-2k,TAK,PITALRE
CyclinK:CCNK,CPR4,MGC9113
CyclinK:CCNK,CPR4,MGC9113
Purity:
≥90%
SpecificActivity:
17pmol/min/µg
Formulation:
50mMTris-HCl,pH7.5,150mMNaCl,0.25mMDTT,0.1mMEGTA,0.1mMEDTA,0.1mMPMSF,25%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Yang,Z.etal:The7SKsmallnuclearRNAinhibitstheCDK9/cyclinT1kinasetocontroltranscription.Nature,2001;414:317-322.
2.Bullrich,F.etal:Chromosomalmappingofmembersofthecdc2familyofproteinkinases,cdk3,cdk6,PISSLRE,andPITALRE,andacdkinhibitor,p27-Kip1,toregionsinvolvedinhumancancer.CancerRes.1995;55:1199-1205.
2.Bullrich,F.etal:Chromosomalmappingofmembersofthecdc2familyofproteinkinases,cdk3,cdk6,PISSLRE,andPITALRE,andacdkinhibitor,p27-Kip1,toregionsinvolvedinhumancancer.CancerRes.1995;55:1199-1205.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Kinase/Serine-Threonine
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
