Bpsbioscience/CDK7/CyclinH1/MNAT1，His标签/40098/10µg
商品编号：
40098
品牌：
bpsbioscience
市场价：
¥7500.00
美元价：
4500.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:40kDa(CDK7),39kDa(CyclinH1),37kDa(MNAT1)
Genbank#:NM_001799,NM_001239,NM_002431
Tag(s):N-terminalHis-tag(CDK7andMNAT1),C-terminalHis-tag(CyclinH1)
a.a:fulllength
Background:
CDK7geneisamemberofthecyclin-dependentproteinkinasefamilythatisimportantregulatorsofcellcycleprogression(1).CDK7formsatrimericcomplexwithcyclinHandMAT1,whichfunctionsasaCDK-activatingkinase(CAK).CDK7isanessentialcomponentofthetranscriptionfactorTFIIHthatisinvolvedintranscriptioninitiationandDNArepair.CDK7isthoughttoserveasadirectlinkbetweentheregulationoftranscriptionandthecellcycle(2).
Description:
ComplexofrecombinanthumanCDK7,CyclinH1andMNAT1,fulllength,withN-terminalHis-tags(CDK7andMNAT1)andC-terminalHis-tag(CyclinH1),(GenBankAccessionNos.NM_001799,NM_001239,andNM_002431respectively),co-expressedinSf9insectcellsviaabaculovirusexpressionsystem.
Synonym(s):
Cyclin-DependentKinase7,CAK1,STK1,CDKN7,p39MO15
CyclinH1:CCNH,CAK,p34,p37
MNATI:MAT1,RNF66
CyclinH1:CCNH,CAK,p34,p37
MNATI:MAT1,RNF66
Purity:
≥80%
SpecificActivity:
21pmol/min/µg
Formulation:
50mMsodiumphosphatepH7.0,300mMNaCl,150mMimidazole,0.1mMPMSF,0.2mMDTT,25%glycerol
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Fisher,R.P.;AnovelcyclinassociateswithMO15/CDK7toformtheCDK-activatingkinase.Cell78:713-724,1994.
2.LaRochelle,S.RequirementsforCdk7intheassemblyofCdk1/cyclinBandactivationofCdk2revealedbychemicalgeneticsinhumancells.Molec.Cell25:839-850,2007.
2.LaRochelle,S.RequirementsforCdk7intheassemblyofCdk1/cyclinBandactivationofCdk2revealedbychemicalgeneticsinhumancells.Molec.Cell25:839-850,2007.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Kinase/Serine-Threonine
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
