Bpsbioscience/ALK1, GST-tag/40018/10 µg
商品编号：
40018
品牌：
bpsbioscience
市场价：
¥7800.00
美元价：
4680.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:64kDa
Genbank#:NM_000020
Tag(s):N-terminalGST-tag
a.a:144–end
Background:
ALK1isaserine/threonine-proteinkinasereceptorR3precursorthatmediatessignalbyTGFβsuperfamily(1).ALK1functionsasaTGFβtypeIreceptorinendothelialcellsandisresponsIBLeforhumanhereditaryhemorrhagictelangiectasia(HHT)typeII.DistinctSmadproteins(i.e.,Smad2/Smad3andSmad1/Smad5)showinteractionwithALK1andmediateTGFβsignaling.NorthernblotandRT-PCRanalysisshowthatALK1specificallyinducesexpressionofSmad6,Smad7,Id1,Id2,endoglin,STAT1,andinterleukin1receptorinendothelialcells.ALK1expressionininflammatorymyofibroblastictumoroftheurinarybladderhavealsohasbeenreported(2).
Description:
Recombinanthumanactivinreceptor-likekinase1,orALK1,(a.a.144-end),withN-terminalGST-tag,expressedinSf9insectcellsviaabaculovirusexpressionsystem.ThegeneaccessionnumberisNM_000020.
Synonym(s):
ACVRL1,ACVRLK1,ALK1,HHT,HHT2,ORW2,SKR3,ALK1,TSR-I
Purity:
≥70%
Formulation:
50mMTris-HCl,pH7.5,150mMNaCl,0.25mMDTT,0.1mMEGTA,0.1mMEDTA,0.1mMPMSF,25%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Ota,T.etal.J.CellPhysiol.2002;193(3):299-318.
2.Tsuzuki,T.etal.Am.J.Surg.Pathol.2004;28(12):1609-14.
2.Tsuzuki,T.etal.Am.J.Surg.Pathol.2004;28(12):1609-14.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Kinase/Serine-Threonine
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
