Bpsbioscience/GSK256066/27751-2/50 mg
商品编号：
27751-2
品牌：
bpsbioscience
市场价：
¥16000.00
美元价：
9600.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:518.6Da
CASRegistry#:801312-28-7
Formula:C27H26N4O5S
Target:PDE4
Description:
GSK256066isaselectivePDE4inhibitorwithanexceptionallyhigh-affinityandselectiveinhibitorofphosphodiesterase4vs.otherPDEisoforms.Oftenusedclinicallybyinhalationinchronicobstructivepulmonarydiseaseandasthma.
Synonym(s):
6-[3-(dimethylcarbamoyl)phenyl]sulfonyl-4-(3-methoxyanilino)-8-methylquinoline-3-carboxamide
BIOLOGicalActivity:
IC50=3.2pMforPDE4B,with>380,000-foldselectivityversusPDE1/2/3/5/6and>2500-foldselectivityagainstPDE4BversusPDE7.GSK256066inhibitsPDE4isoformsA-Dwithequalaffinity.
Solubility:
SolubleinDMSO(>4.6mg/mL).Minimalsolubilityinwater(<1.2mg/mL)
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Tralau-StewartCJ,etal.JPharmacolExpTher,2011,337(1),145-154.
2.WoodrowMD,etal.BioorgMedChemLett,2009,19(17),5261-5265.
2.WoodrowMD,etal.BioorgMedChemLett,2009,19(17),5261-5265.
ScientificCategory:
PDEInhibitor
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
