Bpsbioscience/Doramapimod/27034/25 mg
商品编号：
27034
品牌：
bpsbioscience
市场价：
¥3200.00
美元价：
1920.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW: 527.7 Da
CAS Registry #: 285983-48-4
Formula: C31H37N5O3
Description:
Doramapimod is a protein kinase inhibitor with a >330-fold selectivity for p38 MAPK compared with 12 other protein kinases. Doramapimod prevents both the kinetic activity and phosphorylation of p38 MAPK by binding to the ATP pocket as well as to a novel allosteric binding site on p38 MAPK. Doramapimod also blocks proliferation of cells expressing BCR-ABL(T315I), with an IC50 of 2-3 µM.
Synonym(s):
BIRB 796
Purity:
≥98%
Solubility:
Soluble in DMSO at 50 mg/ml; soluble in ethanol at 30 mg/ml; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20 µM
Format:
White to off-white solid.
Storage / Stability:
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s):
1. Branger, J., et al. J. Immunol. 168: 4070-4077 (2002).
2. Carter, T.A., et al. Proc. Natl. Acad. Sci. USA 102: 11011-11016 (2005).
2. Carter, T.A., et al. Proc. Natl. Acad. Sci. USA 102: 11011-11016 (2005).
Scientific Category:
Kinase
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
