Bpsbioscience/AZD2281 (Olaparib)/27003/25 mg
商品编号：
27003
品牌：
bpsbioscience
市场价：
¥3500.00
美元价：
2100.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:434.5Da
CASRegistry#:763113-22-0
Formula:C24H23FN4O3
Description:
AZD2281,alsoknownasOlaparib,isapoly(ADP-ribose)polymerase1(PARP1)inhibitorandananti-cancerdrugbeingtestedinpatientswithmutationsinthegenesBRCA1orBRCA2.
Synonym(s):
AZD-2281][KU-59436
Purity:
≥95%byHPLC
BIOLOGicalActivity:
Olaparib(AZD2281)isapotentPARPinhibitorwithIC50of1.1nMforPARP1usingtheBPSBiosciencePARP1AssayKit(Cat.#80551).ItinhibitsPARP2withIC50=0.9nMforusingtheBPSBiosciencePARP2AssayKit(Cat.#80552).
Solubility:
SolubleinDMSOat33mg/ml;solubleinethanolat1.7mg/mlwithslightwarming;verypoorlysolubleinwater;maximumsolubilityinplainwaterisestimatedtobeabout10-20µMbuffers,serum,orotheradditivesmayincreaseordecreasetheaqueoussolubility.
Format:
Whitetooff-whitecrystallinesolid;granularorpowder.
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.DeMurcia,J.,etal.,Proc.Natl.Acad.Sci.USA94:7303–7307(1997)
2.Bryant,H.E.,etal.,Nature434:913–915(2005)
3.Farmer,H.,etal.,Nature434:917–921(2005)
2.Bryant,H.E.,etal.,Nature434:913–915(2005)
3.Farmer,H.,etal.,Nature434:917–921(2005)
ScientificCategory:
PARP
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
