Bpsbioscience/Azacytidine (Vidaza)/27107/50 mg
商品编号：
27107
品牌：
bpsbioscience
市场价：
¥4600.00
美元价：
2760.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:244.2Da
CASRegistry#:320-67-2
Formula:C8H12N4O5
Description:
AzacitidineisalsoknownasVidaza,5-azacytidine,Mylosar,andLadakamycin.Azacitidineanditsdeoxyderivative,decitABIne(5-aza-2"deoxycytidine),areusedinthetreatmentofmyelodysplasticsyndrome.TheazacytidineintheDNAformsastablecomplexwithDNAmethyltransferaseenzymes,preventingDNMTactivityandresultinginhypomethylationofcellularDNA.Likewise,theincorporationofazacytidineintoRNAleadstothedissemblyofpolyribosomes,defectivemethylationandinhibitionofproteinproductionwithsubsequentcytotoxicity.
Synonym(s):
Vidaza,5-azacytidine,Mylosar,andLadakamycin
Purity:
≥99%byHPLC
BIOLOGicalActivity:
Whentestinganti-tumoreffectsinprostatecancertheantiproliferativeeffectofazacitidinetreatmentin22rv1cellsandPC3cells,theIC50’swere0.5µMand2.5µMrespectively.
Solubility:
SolubleinDMSO.Insolubleinacetone,ethanol,andmethylethylketone.Slightlysolubleinethanol/watercombinationoffifty-fifty,andpropyleneglycol.
Format:
Whitetooff-whitesolid
Storage/Stability:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
VigushinDMetal.ClinCancerRes.2001Apr;7(4):971-6.
ScientificCategory:
DNMT
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
