Bpsbioscience/Tranylcypromine（2-PCPA）/27305/100 mg
商品编号：
27305
品牌：
bpsbioscience
市场价：
¥3400.00
美元价：
2040.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:364.5kDa
CASRegistry#:13492-01-8
Formula:C18H22N2•H2SO4
Description:
Tranylcypromine(2-PCPA)isanirreversIBLeinhibitorofLSD1histonedemethylaseandmonoamineoxidases(MAO).TheinhibitortargetsmonoamineoxidasesAandBandhasbeenusedasachemicalscaffoldtodesignnewdemethylaseinhibitors.TranylcyprominehasbeenshowntoincreaseHistoneH3lysine4(H3K4)methylationinP19embryonalcarcinomacell.
Purity:
≥98%byHPLC
BIOLOGicalActivity:
TranylcypromineinhibitsLSD1withanIC50valueof20.7µMandaKivalueof242.7µM.ItalsoirreversiblyinhibitsMAOAandMAOBwithIC50valuesof2.3and0.95µMandKivaluesof101.9and16µM,respectively.
Solubility:
Solubleinwater(25mg/ml).
Format:
Awhitetooffwhitesolid
Storage/StABIlity:
Storesolidformat+4°C.Hygroscopic.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Aqueoussolutionsarelessstable;werecommendpreparingandusingstocksolutionsthesameday.
Reference(s):
1.Schmidt,D.M.Z.,andMcCafferty,D.G.etal.Biochemistry46:4408-4416(2007)
2.Yang,M.,etal.Biochemistry46:8058-65(2007)
ApplicationReference(s):
ThelysinedemethylaseLSD1isrequiredfornuclearenvelopeformationattheendofmitosis(2015)
Warning(s):
Hygroscopic.Protectfrommoisture.Protectfromlight.
ScientificCategory:
Demethylase
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
