Bpsbioscience/Mouse JARID1B（KDM5B，PLU-1），标志标签/50122/20µg
商品编号：
50122
品牌：
bpsbioscience
市场价：
¥9000.00
美元价：
5400.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Mouse
HostSpecies:Sf9insectcells
MW:86kDa
Genbank#:NM_152895
Tag(s):N-terminalFLAG-tag
a.a:2–751
Background:
HistonedemethylasethatdemethylatesLys-4ofhistoneH3,therebyplayingacentralroleinhistonecode.DoesnotdemethylatehistoneH3Lys-9orH3Lys-27.Demethylatestrimethylated,dimethylatedandmonomethylatedH3Lys-4.ActsasatranscriptionalcorepressorforFOXG1BandPAX9.FavorstheproliferationofbreastcancercellsbyrepressingtumorsuppressorgenessuchasBRCA1andHOXA5.Incontrast,mayactasatumorsuppressorformelanoma.
Description:
MouseJARID1B,alsoknownasPLU-1andKDM5B(GenBankAccessionNo.NM_152895),a.a.2-751withN-terminalFLAG-tag,MW=86kDa,expressedinSf9cellsviaabaculovirusexpressionsystem.
UniProt
Q80Y84
Synonym(s):
JARID1B,PLU-1,KDM5B,Retinoblastoma-BindingProtein2Homolog1,RBP2-H1,CT31,Cancer/TestisAntigen31,PLU-1,Jumonji,ATRichInteractiveDomain1B,Lysine-SpecificDemethylase5B
Formulation:
45mMTris-HCl,pH8.0,124mMNaCl,2.4mMKCl,90?g/mlFLAGpeptide,10%glycerol,and3mMDTT
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.YamaneK,etal.(2007). Mol.Cell25(6):801–12.
2.BarrettA,etal.(2007). Int.J.Cancer 121(2):265–75.
ApplicationReference:
Anhigh-throughputinvivoscreeningsystemtoselectH3K4-specifichistonedemethylaseinhibitors(2014)
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Demethylase
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
