Bpsbioscience/RGFP966/27643-1/5 mg
商品编号：
27643-1
品牌：
bpsbioscience
市场价：
¥3500.00
美元价：
2100.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:362.4Da
CASRegistry#:1357389-11-7
Formula:C21H19FN4O
Target:HDAC3
Background:
RGFP966isaslow-on/slow-off,competitivetight-bindingHDACinhibitor.RGFP966treatmentontwoCTCLcelllinesfor24hourspriortowesternblotanalysisresultedinincreasedacetylationatH3K9/K14,H3K27,andH4K5,butnotH3K56ac.RGFP966decreasescellgrowthinCTCL(cutaneousTcelllymphoma)celllinesduetoincreasedapoptosisthatisassociatedwithDNAdamageandimpairedSphaseprogression.
Description:
RGFP966isspecificforHDAC3,withanIC50of0.08µMandnoeffectiveinhibitionofanyotherHDACatconcentrationsupto15µM.
Synonym(s):
(E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide
Solubility:
SolubleinDMSO
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.WellsCE,etal.PLoSOne.2013Jul22;8(7):e68915.
2.MalvaezM,etal.ProcNatlAcadSciUSA.2013Feb12;110(7):2647-52.
2.MalvaezM,etal.ProcNatlAcadSciUSA.2013Feb12;110(7):2647-52.
ScientificCategory:
DeacetylaseInhibitor
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
