Bpsbioscience/Panobinostat/27020/5毫克
商品编号：
27020
品牌：
bpsbioscience
市场价：
¥2400.00
美元价：
1440.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW: 349.4 Da
CAS Registry #: 404950-80-7
Formula: C21H23N3O2
Description:
Panobinostat, also known as LBH-589, is a highly active, non-selective HDAC inhibitor. IC50’s against HDAC s 1-9 range between 3 – 61 nM except for a slightly higher IC50 value of 248 nM for HDAC 8. Panobinostat inhibits tumor cell proliferation and induces apoptosis in breast cancer and T cell lymphoma cells. In addition to its tumor-suppressive activities, panobinostat induces histone H3K9 and histone H4K8 acetylation and decreases the level of c-Myc expression.
Synonym(s):
Faridak, LBH-589
Purity:
≥99%
Solubility:
Soluble in DMSO at 200 mg/ml; soluble in ethanol at 5 mg/ml with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 20-50 µM buffers, serum, or other additives may increase or decrease the aqueous solubility.
Format:
Yellow solid
Storage / Stability:
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s):
1. Zhou Q, et al. H Cancer Biol Ther 2007; 6(1):64-69.
2. Ellis L, Pan Y et al. Clin Cancer Res 2008; 14(14):4500-4510.
2. Ellis L, Pan Y et al. Clin Cancer Res 2008; 14(14):4500-4510.
Scientific Category:
HDAC
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
