Bpsbioscience/M344/27203/5毫克
商品编号:
27203
品牌:
bpsbioscience
市场价:
¥2600.00
美元价:
1560.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
MW:307.4Da
CASRegistry#:251456-60-7
Formula:C16H25N3O3
Description:
M344isahistonedeacetylase(HDAC)inhibitoralsoknownasD237orMS344.ItinhibitshumanHDACs,andshowsathree-foldselectivityforinhibitionofHDAC6overHDAC1.M344hasbeenfoundtoincreasethesensitivityofhumansquamouscarcinomacellstorADIation.Ithasalsobeenfoundtopromotecellcyclearrestandapoptosisinhumanovariancancercellsandendometrialcancer.M344canalsoinhibitmaizeHDAC.
Synonym(s):
M344,D237,MS344
Purity:
≥98%byHPLC.
BIOLOGicalActivity:
M344inhibitshumanHDAC6withanIC50of~14nMandHDAC1at~46nM.
Solubility:
Solubleinethanolis~3mg/mland~25mg/mlinDMSOandDMF.Forbiologicalexperiments,dilutetheorganicsolventintoaqueousbuffersorisotonicsaline.
Format:
Acrystallinesolid
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Jung,M.,etal.,J.Med.Chem.1999;42:4669-4679.
2.Remiszewski,S.,etal.,J.Med.Chem.2002;45(4):753-757.
3.Heltweg,B.,etal.,J.Med.Chem.2004.;47:5235-5243.
2.Remiszewski,S.,etal.,J.Med.Chem.2002;45(4):753-757.
3.Heltweg,B.,etal.,J.Med.Chem.2004.;47:5235-5243.
ScientificCategory:
HDAC
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。