Bpsbioscience/HDAC7，GST标签/50007/10µg-免疫在线蚂蚁淘旗下平台

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商品详细Bpsbioscience/HDAC7，GST标签/50007/10µg

Bpsbioscience/HDAC7，GST标签/50007/10µg

商品编号： 50007

品牌： bpsbioscience

市场价： ¥99999999.99

美元价： 99999999.99

产地：美国(厂家直采)

公司：

产品分类：细胞因子

公司分类： cytokine

联系Q Q： 3392242852

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商品介绍

Species:Human

HostSpecies:Sf9insectcells

MW:78kDa

Genbank#:AY302468

Tag(s):N-terminalGST-tag

a.a:518–end

Description:

HumanHDAC7,GenBankAccessionNo.AY302468,a.a.518-end,withN-terminalGST-tag,MW=78kDa,expressedinbaculovirusexpressionsystem.

UniProt

Q8WUI4

Synonym(s):

histonedeacetylase7,HDAC-7

SpecificActivity:

≥15,000pmol/min/µg.

UnitDefinition:

OneU=1pmolofacetylgroupremoved/min/µgofenzyme

AssayConditions:

25mMTrisHCl,pH8.0,137mMNaCl,2.7mMKCl,1mMMgCl₂,and0.1mg/mlBSA,20µMBPSHDACclass2asubstrate(Catalog#50040),andHDAC7(0.16-10ng).Incubationcondition:30minat37°C,followedbyHDACdeveloper(Catalog#50030)for15minatroomtemperature.Fluorescenceintensityismeasuredatex360/em460.

Formulation:

45mMTris-HCl,pH8.0,124mMNaCl,2.4mMKCl,20mMglutathione,and10%glycerol.

Format:

Aqueousbuffersolution

Storage/StABIlity:

>6monthsat-80°C.

Application(s):

Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.

Reference(s):

1.ChakrabortyS.(2006)J.Biol.Chem.281(46):35070-80.
2.Wolfgang,F.(2001)J.Biol.Chem.276(38):35826-35835.

ApplicationReferences:
1. Impactofbindingmechanismonselectiveinhibitionofhistonedeacetylaseisoforms(2017)
2. InSilicoandinVitroInteractionsbetweenShortChainFattyAcidsandHumanHistoneDeacetylases(2017)
3. StructuralCharacterizationoftheSMRTCorepressorInteractingwithHistoneDeacetylase(2017)
4. Design,synthesis,3Dpharmacophore,QSAR,anddockingstudiesofcarboxylicacidderivativesasHistoneDeacetylaseinhibitorsandcytotoxicagents(2014)
5.InVivoImagingofHistoneDeacetylases(HDACs)intheCentralNervousSystemandMajorPeripheralOrgans(2014)
6.AselectiveHDAC1/2inhibitormodulateschromatinandgeneexpressioninbrainandaltersmousebehaviorintwomood-relatedtests(2013)
7.Crebinostat:anovelcognitiveenhancerthatinhibitshistonedeacetylaseactivityandmodulateschromatin-mediatedneuroplasticity(2013)
8.FDG-PETimagingrevealslocalbrainglucoseutilizationisalteredbyclassIhistonedeacetylaseinhibitors(2013)

Warning(s):

Avoidfreeze/thawcycles.

ScientificCategory:

Deacetylase

ProductType:

RecombinantProtein

Datashownislot-specific.Contactusforspecificinformationonotherlots.

品牌介绍

bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。

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