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当前位置: 首页 > 产品中心 > cytokine > Bpsbioscience/HDAC5 (full length), GST-tag/50045/5 µg
商品详细Bpsbioscience/HDAC5 (full length), GST-tag/50045/5 µg
Bpsbioscience/HDAC5 (full length), GST-tag/50045/5 µg
Bpsbioscience/HDAC5 (full length), GST-tag/50045/5 µg
商品编号: 50045
品牌: bpsbioscience
市场价: ¥9300.00
美元价: 5580.00
产地: 美国(厂家直采)
公司:
产品分类: 细胞因子
公司分类: cytokine
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:150kDa
Genbank#:NM_005474
Tag(s):N-terminalGST-tag
a.a:fulllength
Description:
HumanHDAC5,GenBankAccessionNo.NM_005474,fulllengthwithN-terminalGST-tag,MW=150kDa,expressedinbaculovirusexpressionsystem.
UniProt
Q9UQL6
Synonym(s):
histonedeacetylase5,HDAC-5
UnitDefinition:
OneU=1pmolofacetylgroupremoved/min/µgofenzyme
AssayConditions:
25mMTrisHCl,pH8.0,137mMNaCl,2.7mMKCl,1mMMgCl2,and0.1mg/mlBSA,20µMBPSsubstrate(Catalognumber50040),and0.8-50ng/µlHDAC5.Incubationcondition:30minat37°CfollowedbyHDACdeveloper(Catalog#50030)for15minatroomtemperature.Fluorescenceintensityismeasuredatex360/em460.
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,16mMglutathione,20%glycerol
Format:
Aqueousbuffersolution
Storage/StABIlity:

>6monthsat-80°C.

Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):

1.Spiegelberg,B.D.andHamm,H.E.(2005)J.Biol.Chem.280,41769-41776
2.Waltregnyetal.,(2004)J.NeuralTransm.48,273-290.

ApplicationReferences:
1.InVivoImagingofHistoneDeacetylases(HDACs)intheCentralNervousSystemandMajorPeripheralOrgans(2014)
2.AselectiveHDAC1/2inhibitormodulateschromatinandgeneexpressioninbrainandaltersmousebehaviorintwomood-relatedtests(2013)
3.Crebinostat:anovelcognitiveenhancerthatinhibitshistonedeacetylaseactivityandmodulateschromatin-mediatedneuroplasticity(2013)
4.TotalsynthesisandfullhistonedeacetylaseinhibitoryprofilingofAzumamidesA-Easwellasβ²-epi-AzumamideEandβ³-epi-AzumamideE.z

Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Deacetylase
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。