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当前位置: 首页 > 产品中心 > cytokine > Bpsbioscience/HDAC2, FLAG-tag/50052/50 µg
商品详细Bpsbioscience/HDAC2, FLAG-tag/50052/50 µg
Bpsbioscience/HDAC2, FLAG-tag/50052/50 µg
Bpsbioscience/HDAC2, FLAG-tag/50052/50 µg
商品编号: 50052
品牌: bpsbioscience
市场价: ¥8800.00
美元价: 5280.00
产地: 美国(厂家直采)
公司:
产品分类: 细胞因子
公司分类: cytokine
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:60kDa
Genbank#:Q92769
Tag(s):C-terminalFLAG-tag
a.a:fulllength
Description:
HumanHDAC2,GenBankAccessionNo.Q92769,fulllengthwithC-terminalFLAG-tag,MW=60kDa,expressedinbaculovirusexpressionsystem.
UniProt
Q92769
Synonym(s):
histonedeacetylase2,HDAC-2
SpecificActivity:
≥1020pmol/min/µg.
AssayConditions:
25mMofTris-HCl,pH8.0,137mMofNaCl,2.7mMofKCl,1mMofMgCl2,0.1mg/mlBSA,20µMBPSHDACsubstrate3,BPScatalog#:50037,30minat37°C,followedbyHDACdeveloper(Catalog#50030)for15minatroomtemperature.Fluorescenceintensityismeasuredatex360/em460.
Formulation:
45mMTris-HCl,pH8.0,124mMNaCl,2.4mMKCl,90µg/mlFLAGpeptideand10%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:

>6monthsat-80°C.

Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):

1.Yang,W.M.etal.,Proc.Natl.Acad.Sci.U.S.A.93(23),12845-12850(1996).
2.Mungall,A.J.etal.,Nature425(6960),805-811(2003).

ApplicationReference(s):
1.KineticallySelectiveInhibitorsofHistoneDeacetylase2(HDAC2)asCognitionEnhancers(2015)
2.AchimericSERM-histonedeacetylaseinhibitorapproachtobreastcancertherapy(2014)
3.InVivoImagingofHistoneDeacetylases(HDACs)intheCentralNervousSystemandMajorPeripheralOrgans(2014)
4.AselectiveHDAC1/2inhibitormodulateschromatinandgeneexpressioninbrainandaltersmousebehaviorintwomood-relatedtests(2013)
5.ClassIHDACimagingusing[(3)H]CI-994autorADIography(2013)
6.Crebinostat:anovelcognitiveenhancerthatinhibitshistonedeacetylaseactivityandmodulateschromatin-mediatedneuroplasticity(2013)
7.FDG-PETimagingrevealslocalbrainglucoseutilizationisalteredbyclassIhistonedeacetylaseinhibitors(2013)
8.HighlyligandefficientandselectiveN-2-(Thioethyl)picolinamidehistonedeacetylaseinhibitorsinspiredbythenaturalproductpsammaplinA(2013)
9.ImagingepigeneticregulationbyhistonedeacetylasesinthebrainusingPET/MRIwith¹⁸F-FAHA(2013)
10.SantacruzamateA,apotentandselectivehistonedeacetylaseinhibitorfromthePanamanianmarinecyanobacteriumcf.Symplocasp(2013)
11.TotalsynthesisandfullhistonedeacetylaseinhibitoryprofilingofAzumamidesA-Easwellasβ²-epi-AzumamideEandβ³-epi-AzumamideE(2013)

Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Deacetylase
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。