Bpsbioscience/CUDC-907/27616-1/5毫克
商品编号：
27616-1
品牌：
bpsbioscience
市场价：
¥4700.00
美元价：
2820.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:508.6Da
CASRegistry#:1339928-25-4
Formula:C23H24N8O4S
Target:HDAC,PI3K
Background:
CUDC-907hasalonghalf-lifeinmurinetumors.CUDC-907inducesapoptosisandinhibitscancercellproliferationinxenografttumors.
Description:
CUDC-907isadualPI3KandHDACinhibitor
Synonym(s):
N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide
Purity:
≥98%byHPLC
BIOLOGicalActivity:
CUDC-907inhibitsHDAC1,2,3,6,8,10,and11withIC50of1.7nM,5nM,1.8nM,27nM,191nM,2.8nM,and5.4nM,respectively.CUDC-907inhibitsPI3Kα(IC50of19nM)andotherPI3KisoformssuchasPI3Kβ,PI3Kγ,PI3Kδ,PI3KαH1047RandPI3KαE545KwithIC50of54nM,311nM,39nM,73nMand62nM,respectively.CUDC-907suppressesothertypesofHDACenzymaticactivitywithlowerpotency.
Solubility:
SolubleinDMSO
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
QianC,etal.ClinCancerRes.2012Aug1;18(15):4104-13.
ScientificCategory:
DeacetylaseInhibitor
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
