Bpsbioscience/CUDC-101/27022/5 mg
商品编号：
27022
品牌：
bpsbioscience
市场价：
¥3400.00
美元价：
2040.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:434.5Da
CASRegistry#:1012054-59-9
Formula:C24H26N4O4
Description:
CUDC-101isapotentinhibitorofhistonedeacetylase(HDAC)andthereceptorkinasesepidermalgrowthfactorreceptor(EGFR)andhumanepidermalgrowthfactorreceptor2(HER2),withIC50valuesof4.4,2.4,and15.7nM,respectively.ItinhibtedEGFRandHer2phosphorylation,reducedcellproliferationandinducedapoptosisinHCC827non-smallcelllungcancer(NSCLC)xenografts.CUDC-101inhibitedEGFRandinducedupregulationofacetylatedhistoneH3inadose-dependentfashion.
Purity:
≥99%
Solubility:
SolubleinDMSOat28mg/ml;verypoorlysolubleinethanol;verypoorlysolubleinwater;maximumsolubilityinplainwaterisestimatedtobeabout20-50µM;buffers,serum,orotheradditivesmayincreaseordecreasetheaqueoussolubility.
Format:
Whitesolid.
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Wang,J.,etal.MolCancerTher.2013Jun;12(6):925-36.
2.Lai,C.J.,etal.CancerRes.2010May1;70(9):3647-56.
2.Lai,C.J.,etal.CancerRes.2010May1;70(9):3647-56.
ScientificCategory:
HDAC
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
