Bpsbioscience/Human Interferon-alpha 2a/90158-B/100 µg
商品编号：
90158-B
品牌：
bpsbioscience
市场价：
¥4100.00
美元价：
2460.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:19kDa
Genbank#:P01563
a.a:24–188
Background:
AllknownsubtypesofIFN-alphashowthesameantiviralantiparasitic,antiproliferativeactivities.HumanIFN-alphaisalsoapotentantiviralsubstanceinmurine,porcine,andbovinecellsystems.IFN-alphaformsareproducedbymonocytes/macrophages,lymphoblastoidcells,fibroblasts,andanumberofdifferentcelltypesfollowinginductionbyviruses,nucleicacids,glucocorticoidhormones,andlow-molecularweightsubstances.AllIFN-alphasubtypespossessacommonconservedsequenceregionbetweenaminoacidpositions115-151whiletheamino-terminalendsarevariable.ManyIFN-alphasubtypesdifferintheirsequencesatonlyoneortwopositions.IFN-alphaandIFN-betaarethoughttobindtothesamereceptor.SignaltransductionmechanismselicitedafterbindingofIFN-alphatoitsreceptorsinvolvestyrosinephosphorylationofvariousnon-receptortyrosinekinasesbelongingtotheJanuskinases.
Description:
RecombinantInterferonalpha2aisadisulfide-linkedmonomericproteinconsistingof166aminoacidresidues,andmigratesasanapproximately19kDaproteinundernon-reducingconditionsandreducingconditionsinSDS-PAGE.OptimizedDNAsequenceencodingHumanInterferon-alphamaturechainwasexpressedinE.coli.
UniProt
P01563
Synonym(s):
InterferonAlpha2a,IFN2a,IFNA,IFNalpha,IFN
Purity:
≥98%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BIOLOGicalActivity:
The activitywasdeterminedby aviralresistanceassay ofHumanWISHcells,and wasfoundtobeintherangeof 1x108IU/mg.
Formulation:
Lyophilizedfrom0.2µmfilteredPBSsolution,pH7.0.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/StABIlity:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.J.Biol.Chem.,Sep2009,284:25051-25064.
2.J.Biol.Chem.,Sep2009,284:24328-24340.
2.J.Biol.Chem.,Sep2009,284:24328-24340.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
CDLPQTHSLGSRRTLMLLAQMRKISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
