Bpsbioscience/Human Growth Hormone 192AA/90142-B/500 µg
商品编号：
90142-B
品牌：
bpsbioscience
市场价：
¥4100.00
美元价：
2460.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:22kDa
Genbank#:P01241
a.a:27–217
Background:
Thephysiologicalactivityforwhichgrowthhormoneisbestknownisthepromotionofgrowthofbone,cartilage,andsofttissues.Detectablelevelsofgrowthhormonearefoundthroughouttheremainderofadulthood,suggestingotherfunctionsinadditiontopromotionofgrowth.Growthhormonemaybeimportantforthemaintenanceofleanbodymass,mostgrowth-promotingeffectsofgrowthhormonearemediatedbyIGF-1thesynthesisofwhichisregulatedbygrowthhormone.TheBIOLOGicalactivitiesofgrowthhormonearemediatedbyreceptorsbelongingtooneofthecytokinereceptorfamilies.GrowthhormonehasbeenshowntobeproducedbyT-cells,B-cells,andmacrophages.Inhumanlymphocytes,growthhormoneappearstoup-regulateitsownexpression.GrowthhormoneappearstoactasanenhancerofimmuneresponsesandisproducedinconsiderableamountsbyT-helpercells.
Description:
Recombinanthumangrowthhormoneisadisulfide-linkedmonomericproteinconsistingof192a.a.andmigratesasanapproximately22kDaproteinunderreducingandnon-reducingconditions.OptimizedDNAsequenceencodinghumangrowthhormonematurechainwasexpressedinE.coli.
UniProt
P01241
Synonym(s):
growthhormone,GH1,Somatotropin
Purity:
≥95%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BiologicalActivity:
Determinedbyadose-dependentcellproliferationassayusingtheratlymphoma,Nb2-11,tobeintherangeof0.1ng/ml.
Formulation:
Lyophilizedfroma0.2µmfilteredsolutionof5µMNaHCO3,pH10.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/StABIlity:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.Pediatrics.Nov.2010,126(5):e1211-26.
2.HandbookExp.Pharmacol.2010,(195):187-200.
3.HormRes.Nov.2009,72Suppl1:60-4.
2.HandbookExp.Pharmacol.2010,(195):187-200.
3.HormRes.Nov.2009,72Suppl1:60-4.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
