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当前位置: 首页 > 产品中心 > cytokine > Bpsbioscience/Human GRO-gamma (CXCL3)/90151-B/10 µg
商品详细Bpsbioscience/Human GRO-gamma (CXCL3)/90151-B/10 µg
Bpsbioscience/Human GRO-gamma (CXCL3)/90151-B/10 µg
Bpsbioscience/Human GRO-gamma (CXCL3)/90151-B/10 µg
商品编号: 90151-B
品牌: bpsbioscience
市场价: ¥4100.00
美元价: 2460.00
产地: 美国(厂家直采)
公司:
产品分类: 细胞因子
公司分类: cytokine
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:8kDa
Genbank#:P19876
a.a:35–107
Background:
Growthregulatedoncogene-gammabelongstothefamilyofchemotycticcytokinescalledchemokines.ItisidenticalwithMGSA(melanomagrowthstimulatoryactivity)andthenewdesignationisCXCL3.Thisfactorisknownmainlybecauseofitschemotacticactivity.GROexpressionisinducIBLebyserumorPDGFand/orbyavarietyofinflammatorymediators,suchasIL-1andTNF,inmonocytes,fibroblasts,melanocytesandepithelialcells.Incertaintumorcelllines,GROisexpressedconstitutively.Similartootheralphachemokines,thethreeGROproteinsarepotentneutrophilattractantsandactivators.Inaddition,thesechemokinesarealsoactivetowardbasophils.AllthreeGROscanbindwithhighaffinitytotheIL-8receptortypeB.
Description:
RecombinantGRO-gammaisadisulfide-linkedhomodimericproteinconsistingof74aminoacidresidues,andmigratesasanapproximately8kDaproteinundernon-reducingandreducingconditionsinSDS-PAGE.OptimizedDNAsequenceencodinghumanGRO-gamma(CXCL3)maturechainwasexpressedinE.coli.
UniProt
P19876
Synonym(s):
CXCL3,GRO-gamma,MIP2B,MGSA-gamma
Purity:
≥95%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BIOLOGicalActivity:
DeterminedbyitsABIlitytochemoattract293transfectedCXCR2cellsusingaconcentrationrangeof10-100ng/ml.
Formulation:
Lyophilizedfrom0.2µmfilteredconcentrated(1mg/ml)solutionin100mMNaCl,20mMphosphatebuffer,pH7.5.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/Stability:

Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.

Reference(s):
1.Al-AlwanLA,etal.JImmunol.2013Sep1,191(5):2731-41.
2.AdrogueHE,etal.AmJNephrol.2007,27(3):253-61.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
ASVVTELRCQCLQTLQGIHLKNIQSVNVRSPGPHCAQTEVIATLKNGKKACLNPASPMVQKIIEKILNKGSTN
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。