Bpsbioscience/Human Erythropoietin-alpha/90257-B/50 µg
商品编号：
90257-B
品牌：
bpsbioscience
市场价：
¥4100.00
美元价：
2460.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Hamster
MW:35kDa
Genbank#:P01588
a.a:28–193
Background:
EPOispredominantlysynthesizedandsecretedbytubularandjuxtatubularcapillaryendothelialandinterstitialcellsofthekidney.Approximately10-15%ofthetotalamountofEpocomesfromextrarenalsourcesandispredominantlyproducedbyhepatocytesandKupffercellsoftheliver.Approximately40%ofthemolecularmassofEpoisduetoitsglycosylation.GlycosylationisanimportantfactordeterminingthepharmacokineticbehaviorofEpoinvivo.Non-glycosylatedEpohasanextremelyshortBIOLOGicalhalflife.Itstillbindstoitsreceptorandmayevenhaveahigherspecificactivityinvitro.
Description:
RecombinantEPO-aisaglycosylateddisulfide-linkedhomodimericproteinconsistingof166aminoacidresidues,andmigratesasanapproximately35kDaproteinunderreducingconditionsinSDS-PAGE.OptimizedDNAsequenceencodingHumanEPOmaturechainwasexpressedinChineseHamsterOvary(CHO)cells.
UniProt
P01588
Synonym(s):
EPO,erythropoietin,
Purity:
≥98%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
BiologicalActivity:
Activitywasdeterminedbythedose-dependentproliferationassayusingafactor-dependenthumanerythroleukemiccelllineTF-1andwasfoundtobe3.8x105IU/mg.
Formulation:
Lyophilizedfrom0.2µmfilteredPBSsolution,pH7.0.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Reference(s):
J.Biol.Chem.,Sep2009,284:26988-26998.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
APPRLICDSRVLERYLLEAKEAENITTGCAEHCSLNENITVPDTKVNFYAWKRMEVGQQAVEVWQGLALLSEAVLRGQALLVNSSQPWEPLQLHVDKAVSGLRSLTTLLRALGAQKEAISPPDAASAAPLRTITADTFRKLFRVYSNFLRGKL
KLYTGEACRTGDR
KLYTGEACRTGDR
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
