Bpsbioscience/人β-防御素-2/90107-B/20µg
商品编号：
90107-B
品牌：
bpsbioscience
市场价：
¥4100.00
美元价：
2460.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:4kDa
Genbank#:O15263
a.a:24–64
Background:
Defensinsarealargefamilyofpeptidesofwhichtwogroupsexistinmammals:alphadefensinsandbetadefensins,whicharedistinguishablebythespacingandconnectivityoftheconservedcysteineresidueswithinthematurepeptides.ItisthoughtthatdefensinsfunctionintheerADIcationofpathogensfromthehostsystembyinsertingthemselvesintothebacterialmembraneundertheinfluenceofmembranepotential,formingchannelswhichleadtoleakageofcytoplasmicmoleculesandcelldeath.UnlikehBD-1,thissecondpeptide,humanbeta-defensin-2(hBD-2),isregulatedatatranscriptionallevelinresponsetocontactwithmicroorganisms,andishighlyeffectiveinkillingGramnegativebacteria.Itsexpressionisalsoupregulatedbythecytokinetumornecrosisfactor-alpha.
Description:
RecombinantbetaDefensin-2isadisulfide-linkedmonomerproteinconsistingof42aminoacidresidues,andmigratesasanapproximately4kDaproteinundernon-reducingandreducingconditionsinSDS-PAGE.OptimizedDNAsequenceencodingHumanbetaDefensin-2maturechainwasexpressedinE.coli.
UniProt
O15263
Synonym(s):
BD2,betadefensin2,DEFB4
Purity:
≥98%bySDS-PAGEandHPLC
EndotoxinLevel:
<0.1ng/µg(1EU/µg),usingtheLALgelclotmethod.
Formulation:
Lyophilizedfrom0.2µmfiltered100mMNaCl,20mMphosphatebuffer,pH7.4.
Format:
lyophilizedprotein
Reconstitution:
Reconstituteat0.1-1.0mg/mlindistilledwater.Thissolutioncanthenbedilutedintootherbuffers.Tomaximizeproductcollectionfromvialsurface,vortexbrieflyandthenspindowntorecollecttheliquid.
Storage/Stability:
Thelyophilizedproteinisstableforatleast2yearsfromdateofreceiptwhenstoredat-20°C.Uponreconstitution,storeinworkingaliquotsat+4°Cforuptoonemonth,orat-20°Cforuptosixmonths,inthepresenceofacarrierprotein.Avoidrepeatedfreeze/thawcycles.
Reference(s):
1.J.Biol.Chem.,Apr2009,284:10034-10045.
2.J.Immunol.,Feb2009,182:1609-1616.
3.Endocrinology,Oct2008,149:5189-5198.
2.J.Immunol.,Feb2009,182:1609-1616.
3.Endocrinology,Oct2008,149:5189-5198.
Warning(s):
Avoidfreeze/thawcycles
AminoAcidSequence:
GIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
ScientificCategory:
Cytokine/GrowthFactors
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
