Bpsbioscience/人BCMA（CD269）/90105-A/5µg
商品编号：
90105-A
品牌：
bpsbioscience
市场价：
¥1640.00
美元价：
984.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species: Human
Host Species: E. coli
MW: 6 kDa
Genbank #: Q02223
a.a: 1–54
Background:
BCMA (B cell maturation) is a nonglycosylated integral membrane type I protein that is preferentially expressed in mature B lymphocytes. The N-terminal part of both mouse and human proteins contains a conserved six- cysteine motif. BLyS binds to three receptors of the TNF receptor family (B cell maturation antigen BCMA, TACI, and BAFF-R), all of which are expressed by mature B cells.
Description:
Recombinant human BCMA (B cell maturation antigen), also known as CD269, is a disulfide-linked monomeric protein consisting of 54 a.a. and migrates as an approximately 6 kDa protein under reducing and non-reducing conditions. Source: Optimized DNA sequence encoding human BCMA extracellular domain was expressed in E. coli. Formulation: Reconstitution: Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. S
UniProt
Q02223
Synonym(s):
BCMA, B cell maturation antigen, CD269
Purity:
≥95% by SDS-PAGE and HPLC
Endotoxin Level:
<0.1 ng/µg (1 EU/µg), using the LAL gel clot method.
Formulation:
Lyophilized from a 0.2 µm filtered solution containing 30% acetonitrile, 0.1% TFA solution, pH 7.5.
Format:
lyophilized protein
Reconstitution:
Reconstitute at 0.1-1.0 mg/ml in distilled water. This solution can then be diluted into other buffers. To maximize product collection from vial surface, vortex briefly and then spin down to recollect the liquid.
Storage / Stability:
The lyophilized protein is stable for at least 2 years from date of receipt when stored at -20°C. Upon reconstitution, store in working aliquots at +4°C for up to one month, or at -20°C for up to six months, in the presence of a carrier protein. Avoid repeated freeze/thaw cycles.
Reference(s):
1. Activation of B-cell maturation antigen (BCMA) on human multiple myeloma cells by a proliferation-inducing ligand (april) promotes myeloma cell function in the bone marrow microenvironment. Blood (ASH Annual Meeting Abstracts), Nov 2007, 110: 1503.
2. Autoantibody-producing rp105– B cells, from patients with systemic lupus erythematosus, showed more preferential expression of BCMA compared with BAFF-R than normal subjects. Rheumatology, Jan 2010, 10: 1093.
2. Autoantibody-producing rp105– B cells, from patients with systemic lupus erythematosus, showed more preferential expression of BCMA compared with BAFF-R than normal subjects. Rheumatology, Jan 2010, 10: 1093.
Warning(s):
Avoid freeze/thaw cycles
Amino Acid Sequence:
MLQMAGQCSQ NEYFDSLLHA CIPCQLRCSS NTPPLTCQRY CNASVTNSVK GTNA
Scientific Category:
Cytokine/Growth Factors
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
