![Bpsbioscience/CTLA4[生物素化]：B7-2抑制剂筛选分析试剂盒/72024/96反应](https://www.ebiomall.cn/images/bpsbioscience/201712/72024_graph1.png)
Bpsbioscience/CTLA4[生物素化]：B7-2抑制剂筛选分析试剂盒/72024/96反应
商品编号：
72024
品牌：
bpsbioscience
市场价：
¥21500.00
美元价：
12900.00
产品分类：
其它检测试剂盒
公司分类：
Other_kits
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Background:
B7-2(CD86)signalingthroughCTLA4(CD152)hasbeenshowntoinhibitTcellactivation.Thisco-inhibitorypathwaycanbeoveractiveinmanytumors,enablingcancerstoescapethehost’simmunesystem.CTLA4-blockingantibodies,includingIpilimumab(Yervoy)andTremelimumab,haveshownclinicalefficacyintreatingcancer.
Description:
TheCTLA4[Biotinylated]:B7-2InhibitorScreeningAssayKitisdesignedforscreeningandprofilinginhibitorsofCTLA4:B7-2interaction.Thekeytothiskitisthehighsensitivityofdetectionofbiotin-labeledCTLA4bystreptavidin-HRP.Onlyafewsimplestepsonamicrotiterplatearerequiredfortheassay.First,B7-2iscoatedona96-wellplate.Next,CTLA4-biotinisincubatedwithB7-2ontheplate.Finally,theplateistreatedwithstreptavidin-HRPfollowedbyadditionofanHRPsubstratetoproducechemiluminescence,whichcanthenbemeasuredusingachemiluminescencereader.
Synonym(s):
T-lymphocyteactivationantigenCD86,B7.2,FUN-1,B70,BU63,CD86,CytotoxicT-lymphocyte-associatedprotein4,CD152
SuppliedAs:
Thiskitcomesinaconvenient96-wellformat,withbiotin-labeledCTLA4(CD152),purifiedB7-2(CD86),streptavidin-labeledHRP,andassaybufferfor100bindingreactions
Format:
Instructionsforuse:
Seeassaykitdatasheetfordetailedprotocol
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival
Application(s):
ThiskitisusefulforscreeningforinhibitorsofCTLA4bindingtoB7-2.
Reference(s):
1.Ohtani,H.,etal.,LabInvest.1997;77(3):231-241.
2.Rovert,C.,etal.,N.Engl.J.Med.2011;364:2517-25262.
2.Rovert,C.,etal.,N.Engl.J.Med.2011;364:2517-25262.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Immunotherapy/CellSurfaceReceptor
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
