4000-520-616
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4000-520-616
当前位置: 首页 > 产品中心 > Routine_cell_strain > Bpsbioscience/CFTR–HEK 293重组细胞系/60506/2小瓶
商品详细Bpsbioscience/CFTR–HEK 293重组细胞系/60506/2小瓶
Bpsbioscience/CFTR–HEK 293重组细胞系/60506/2小瓶
Bpsbioscience/CFTR–HEK 293重组细胞系/60506/2小瓶
商品编号: 60506
品牌: bpsbioscience
市场价: ¥150000.00
美元价: 90000.00
产地: 美国(厂家直采)
公司:
产品分类: 常规细胞株
公司分类: Routine_cell_strain
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Species:Human
Genbank#:P13569
Background:
Cysticfibrosistransmembraneconductanceregulator(CFTR)isaproteinthatinhumansisencodedbytheCFTRgene.CFTRisanABCtransporter-classionchannelthattransportschlorideandthiocyanateionsacrossepithelialcellmembranes.MutationsoftheCFTRgeneaffectfunctioningofthechlorideionchannelsinthesecellmembranes,leADIngtocysticfibrosis.Itischaracterizedbythetriadofchronicbronchopulmonarydisease(withrecurrentrespiratoryinfections),pancreaticinsufficiency(whichleadstomalabsorptionandgrowthretardation)andelevatedsweatelectrolytes.
Description:
TheCFTR-HEK293CellLinestablyexpressesfulllength,humancysticfibrosistransmembraneconductanceregulator(CFTR)protein(GenBank#P13569).Asyntheticcodon-optimizedDNAsequenceencodinghumanCFTRproteinwithC-terminalStreptavidin-BindingPeptide(SBP)tagisstablyintegratedin293HEK-Trexcells.
Synonym(s):
CFTR,cysticfibrosistransmembraneconductanceregulator
SuppliedAs:
Eachvialcontains~2X106cellsin1mlofSigmaFreezingMedium(Cat.#C-6164).
BIOLOGicalActivity:
TheexpressionofCFTRisconfirmedbyWesternblottingandflowcytometry(FACS).
HostCellline:
HEK293cells
Instructionsforuse:
Seecelllinedatasheetfordetailedculturingandassayprotocol.
Storage/StABIlity:

Storeinliquidnitrogenimmediatelyuponreceipt.Cellsarestableafteraminimumofsevencontinuouspassages.Uponfirstuse,amplifythecellsincultureandmakeseveralfrozenaliquotsforfutureuse.

Application(s):
•DrugcompoundscreeningforactivatorsorinhibitorsofCFTR
•FunctionalassaysforCFTR
•Efficientantigenformouseimmunization
Reference(s):
1.Gadsby,D.C.,etal.Nature440(7083):477–483(2006).
2.Hillier,L.W.,etal.Nature424:157-164(2003).
3.McCann,C.M.,etal.BioTechniques38(6):945–952(2005).
Notes:

Contactusforpricing.

LicenseDisclosure:Purchaseofthiscelllinegrantsyouwitha10-yearlicensetousethiscelllineinyourimmediatelaboratory,forresearchuseonly.Thislicensedoesnotpermityoutoshare,distribute,sell,sublicense,orotherwisemakethecelllineavailableforusetootherlaboratories,departments,researchinstitutions,hospitals,universities,orbiotechcompanies.Thelicensedoesnotpermituseofthiscelllineinhumansorfortherapeuticordruguse.Thelicensedoesnotpermitmodificationofthecelllineinanyway.InappropriateuseordistributionofthiscelllinewillresultinrevocationofthelicenseandresultinanimmediateceaseofsalesanddistributionofBPSproductstoyourlaboratory.BPSdoesnotwarrantthesuitabilityofthecelllineforanyparticularuse,anddoesnotacceptanyliabilityinconnectionwiththehandlingoruseofthecellline.Modificationsofthiscellline,transfertoanotherfacility,orcommercialuseofthecellsmayrequireaseparatelicenseandadditionalfees;contactsales@bpSBIoscience.comfordetails.PublicationsusingthiscelllineshouldreferenceBPSBioscience,Inc.,SanDiego.

Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
ionchannel
ProductType:
CellLine
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。