Bpsbioscience/CD47:SIRP-γ[生物素化]抑制剂筛选分析试剂盒/72059/96反应
商品编号:
72059
品牌:
bpsbioscience
市场价:
¥21400.00
美元价:
12840.00
产品分类:
其它检测试剂盒
公司分类:
Other_kits
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Background:
Signal-regulatoryproteingamma(SIRP-λ),alsoknownasCD172g,isacellsurfaceproteinexpressedmainlybymyeloidcellssuchasmacrophages.Itsreceptor,CD47,isubiquitouslyexpressedonthesurfaceofallcellsandhasbeenfoundtobeoverexpressedinsomecancers.CD47bindingtoSIRP-λhasbeenshowntobeimportantforTcelltrans-endothelialmigration(TEM).
Description:
TheCD47:SIRP-γ[Biotinylated]InhibitorScreeningAssayKitisdesignedforscreeningandprofilinginhibitorsofCD47:SIRP-γsignaling.Thekeytothiskitisthehighsensitivityofdetectionofbiotin-labeledSIRP-γthroughstreptavidin-HRP.Onlyafewsimplestepsonamicrotiterplatearerequiredfortheassay.First,CD47iscoatedona96-wellplate.Next,SIRP-γisincubatedwithCD47ontheplate.Finally,theplateistreatedwithstreptavidin-HRPfollowedbyadditionofanHRPsubstratetoproducechemiluminescence,whichcanbemeasuredusingachemiluminescencereader.
Synonym(s):
leukocytesurfaceantigenCD47,Rh-relatedantigen,integrin-associatedprotein(IAP),antigenicsurfacedeterminantproteinOA3,MER6,Signalregulatoryprotein-gamma,signalregulatoryproteinbeta2,andCD172g
Format:
Storage/StABIlity:
Thiskitcomesinaconvenient96-wellformat,withbiotin-labeledSIRP-γ(CD172g),purifiedCD47,streptavidin-labeledHRP,andassaybufferfor100bindingreactions.Stableforoneyearfromdateofreceiptwhenstoredasdirected.
Application(s):
ThiskitisusefulforscreeningforinhibitorsofSIRP-γbindingtoCD47.
Reference(s):
1.Stefanidakis,etal.,Blood.2008,112(4):1280-1289
2.Sick,E.,etal.BrJPharmacol.2012,167(7):1415-1430.
ScientificCategory:
Immunotherapy,CellSurfaceReceptors
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。