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Bpsbioscience/CD28:B7-2[Biotinylated] Inhibitor Screening Assay Kit/72062/96 reactions
Bpsbioscience/CD28:B7-2[Biotinylated] Inhibitor Screening Assay Kit/72062/96 reactions
商品编号:
72062
品牌:
bpsbioscience
市场价:
¥21400.00
美元价:
12840.00
产品分类:
其它检测试剂盒
公司分类:
Other_kits
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Background:
TheactivationofnaïveTcellsrequirestwosignals;thespecificTcellreceptorrecognitionofMHC/Antigenonthesurfaceoftheantigen-presentingcell(APC),andthebindingofB7-2(CD86)ligandontheAPCwiththeCD28receptorontheTcellsurface.CD28:B7-2interactionisanimportantdrugtargetfortheregulationofTcellsinvolvedinautoimmunity,inflammation,tumorrecognition,andimmunetolerance.
Description:
TheCD28:B7-2[Biotinylated]InhibitorScreeningAssayKitisdesignedforscreeningandprofilinginhibitorsofCD28:B7-2signaling.Thekeytothiskitisthehighsensitivityofdetectionofbiotin-labeledB7-2bystreptavidin-HRP.Onlyafewsimplestepsonamicrotiterplatearerequiredfortheassay.First,CD28iscoatedona96-wellplate.Next,B7-2isincubatedwithCD28ontheplate.Finally,theplateistreatedwithstreptavidin-HRPfollowedbyadditionofanHRPsubstratetoproducechemiluminescence,whichcanbemeasuredusingachemiluminescencereader.
Synonym(s):
T-Cell-SpecificSurfaceGlycoprotein,TP44,T-lymphocyteactivationantigenCD86,B7.2,FUN-1,B70,BU63,CD86
SuppliedAs:
Thiskitcomesinaconvenient96-wellformat,withbiotin-labeledB7-2,purifiedCD28,streptavidin-labeledHRP,andassaybufferfor100bindingreactions.
Format:
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.
Reference(s):
1.Keir,M.E.,etal.Immunol.Rev.2005,204:128-143.
2.Yao,S.,etal.Immunity2011,34(5):729-40.
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品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。