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Bpsbioscience/CD137[Biotinylated]:CD137L Inhibitor Screening Assay Kit/72025/96 reactions
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Bpsbioscience/CD137[Biotinylated]:CD137L Inhibitor Screening Assay Kit/72025/96 reactions
商品编号：
72025
品牌：
bpsbioscience
市场价：
¥20500.00
美元价：
12300.00
产品分类：
其它检测试剂盒
公司分类：
Other_kits
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Background:
CD137,alsoknownas4-1BB,isaprototypeco-stimulatorymoleculeexpressedonTcells.CD137interactionwithitscognateligand,CD137L,alsoknownas4-1BBL,resultsinincreasedsT-cellactivationandproliferation.AccumulatingevidenceshowsaroleforCD137:CD137Lsignalingininflammation,suggestingthatinhibitionofthispathwaymayprovideatherapeuticavenuetotreatautoimmuneandinflammatorydiseases.
Description:
TheCD137:CD137LInhibitorScreeningAssayKitisdesignedforscreeningandprofilinginhibitorsofCD137:CD137Linteraction.Thekeytothiskitisthehighsensitivityofdetectionofbiotin-labeledCD137bystreptavidin-HRP.Onlyafewsimplestepsonamicrotiterplatearerequiredfortheassay.First,CD137Liscoatedona96-wellplate.Next,CD137-biotinisincubatedwithCD137Lontheplate.Finally,theplateistreatedwithstreptavidin-HRPfollowedbyadditionofanHRPsubstratetoproducechemiluminescence,whichcanthenbemeasuredusingachemiluminescencereader.
Synonym(s):
4-1BB,TumorNecrosisFactorReceptorSuperfamilymember9,TNFRSF9,ILA,4-1BBligand,4-1BBL,tumornecrosisfactorligandsuperfamilymember9,TNFSF9
SuppliedAs:
Thiskitcomesinaconvenient96-wellformat,withbiotin-labeledCD137,purifiedCD137L,streptavidin-labeledHRP,andassaybufferfor100bindingreactions.
Format:
COMPONENTS:
Instructionsforuse:
Seeassaykitdatasheetfordetailedprotocol
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.
Application(s):
ThiskitisusefulforscreeningforinhibitorsofCD137bindingtoCD137L.
Reference(s):
1.Drenkard,D.,etal.,FASEBJ.2007;21:456-463
2.Kwon,B.,etal.,ImmuneNetw.2009;9(3):84-89.
2.Kwon,B.,etal.,ImmuneNetw.2009;9(3):84-89.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Immunotherapy/CellSurfaceReceptor
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
