Bpsbioscience/TDO细胞检测试剂盒/72033/100反应
商品编号：
72033
品牌：
bpsbioscience
市场价：
¥11300.00
美元价：
6780.00
产品分类：
常规细胞株
公司分类：
Routine_cell_strain
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Background:
L-tryptophan(L-Trp)isanessentialaminoacidnecessaryforproteinsynthesisinmammaliancellsandtheL-Trptokynurenine(Kyn)pathwayisfirmlyestablishedasakeyregulatorofinnateandadaptiveimmunity.CatabolismofL-TrptoKynmaintainsanimmunosuppressivemicroenvironmentbystarvingimmunecellsofL-TrpandreleasingdegradationproductsofL-Trpthathaveimmunosuppressivefunctions.Tryptophan2,3dioxygenase(TDO),oneoftheratelimitingenzymesinthispathway,isupregulatedinmanytumors,providingcancercellswithanavenueforimmuneevasion.
Description:
ThehumanTDOCell-BasedAssayKitisdesignedtomonitortheactivityofexogenouslyexpressedhumanTDOinculturedcells.
Synonym(s):
Tryptophan2,3-dioxygenase,TDO2,TDO-2,TDO
SuppliedAs:
Thekitcontainsatransfection-readyexpressionvectorforfulllengthhumanTDO(hTDO).Uponexpression,hTDOcanconvertL-TrptoKyn,whichgetsreleasedandisdetectedintheassaymedium.Thekitalsoincludesspecializedassaymedium.
Format:
COMPONENTS:
Instructionsforuse:
Seeassaykitdatasheetfordetailedprotocol.
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.
Application(s):
ScreenforinhibitorsofhTDOenzymeinacellularcontext.
Reference(s):
1.Yue,E.,etal.,J.Med.Chem.2009;52:7364–7367.
2.Liu,X.,etal.,Blood.2010;115(17):3520-3530.
2.Liu,X.,etal.,Blood.2010;115(17):3520-3530.
Warning(s):
Avoidfreeze/thawcycles.
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
