Bpsbioscience/PHIP (BD1), His-tag/31140/100 µg
商品编号：
31140
品牌：
bpsbioscience
市场价：
¥6100.00
美元价：
3660.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species: Human
Host Species: E. coli
MW: 17 kDa
Genbank #: NM_017934
Tag(s): N-terminal His-tag
a.a: 1146 – 1287
Background:
PHIP is a bromodomain-containing protein that binds the pleckstrin homology (PH) domain of insulin receptor substrate-1 (IRS1 ), modulates insulin signaling, and plays a role in pancreatic beta cell growth and survival. It stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation.
Description:
Human bromodomain pleckstrin homology domain interacting protein (PHIP), also known as IRS-1 PH Domain-Binding Protein, WDR11, and BRWD2, GenBank Accession No. NM_017934, a.a. 1146 - 1287 corresponding to bromodomain 1, with N-terminal His-tag, MW = 17 kDa, expressed in an E. coli cell expression system.
UniProt
Q8WWQ0
Synonym(s):
bromodomain pleckstrin homology domain interacting protein, IRS-1 PH Domain-Binding Protein, WDR11, BRWD2
Formulation:
40 mM Tris-HCl, pH 8, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
Store at -80°C. Stable for >6 months when stored as directed.
Application(s):
Useful for the study of bromodomain binding assays, screening inhibitors, and selectivity profiling.
Reference(s):
1. De Semir, D., et al., Proc. Natl. Acad. Sci. USA. 2012 May 1;109(18):7067-72.
2. Farhang-Fallah, J., et al., J. Biol. Chem. 2000 Dec 22;275(51):40492-7.
2. Farhang-Fallah, J., et al., J. Biol. Chem. 2000 Dec 22;275(51):40492-7.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Bromodomain
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
