Bpsbioscience/PHIP（BD1），GST标签/31142/100µg
商品编号：
31142
品牌：
bpsbioscience
市场价：
¥6100.00
美元价：
3660.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:43kDa
Genbank#:NM_017934
Tag(s):N-terminalGST-tag
a.a:1146–1287
Background:
PHIPisabromodomain-containingproteinthatbindsthepleckstrinhomology(PH)domainofinsulinreceptorsubstrate-1(IRS1),modulatesinsulinsignaling,andplaysaroleinpancreaticbetacellgrowthandsurvival.Itstimulatescellproliferationthroughregulationofcyclintranscriptionandhasananti-apoptoticactivitythroughAKT1phosphorylationandactivation.
Description:
Humanbromodomainpleckstrinhomologydomaininteractingprotein(PHIP),alsoknownasIRS-1PHDomain-BindingProtein,WDR11,andBRWD2,GenBankAccessionNo.NM_017934,a.a.1146-1287correspondingtobromodomain1,withN-terminalGST-tag,MW=43kDa,expressedinanE.colicellexpressionsystem.
UniProt
Q8WWQ0
Synonym(s):
bromodomainpleckstrinhomologydomaininteractingprotein,IRS-1PHDomain-BindingProtein,WDR11,BRWD2
Formulation:
40mMTris-HCl,pH8,110mMNaCl,2.2mMKCl,0.04%Tween-20,and20%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
Storeat-80°C.Stablefor>6monthswhenstoredasdirected.
Application(s):
Usefulforthestudyofbromodomainbindingassays,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.DeSemir,D.,etal.,Proc.Natl.Acad.Sci.USA.2012May1;109(18):7067-72.
2.Farhang-Fallah,J.,etal.,J.Biol.Chem.2000Dec22;275(51):40492-7.
2.Farhang-Fallah,J.,etal.,J.Biol.Chem.2000Dec22;275(51):40492-7.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Bromodomain
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
