Bpsbioscience/NAD+, Biotin-Labeled/80610/500 µl -免疫在线蚂蚁淘旗下平台

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商品详细Bpsbioscience/NAD+, Biotin-Labeled/80610/500 µl

Bpsbioscience/NAD+, Biotin-Labeled/80610/500 µl

商品编号： 80610

品牌： bpsbioscience

市场价： ¥6600.00

美元价： 3960.00

产地：美国(厂家直采)

公司：

产品分类：细胞因子

公司分类： cytokine

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

MW:1180.1Da

CASRegistry#:53-84-9(NAD+)

Background:

ActivatedPARPcleavesNAD+tonicotinamideandADP-riboseandpolymerizestheADP-riboseonnuclearacceptorproteinssuchashistones,transcriptionfactors,andPARPitself.BiotinylatedNAD+(6-Biotin-17-NAD+)providesanon-isotopicalternativetorADIolabeledNAD+forassaysrequiringthissubstrate.BiotinylatedNAD+canbeusedasanindirectmeasureofPARPactivitywhenbiotinincorporationisdetectedusingastreptavidindetectionsystem.BiotinylatedNAD+isalsousefulforlabelingorpurifyingproteinsviapoly(ADP)ribosylation.

Description:

NAD+covalentlylabeledwithbiotin(6-biotin-17-nicotinamide-adenine-dinucleotide),orNAD+Biotin-Labeled.Canbeusedasasubstratebypoly(ADP-ribosyl)polymerase(PARP)enzymesforgeneratingbiotin-labeledADP-ribosemonomersinPARylationreactions.

Synonym(s):

6-Biotin-17-NAD+,BiotinNicotinamideadeninedinucleotide,β-Nicotinamide-N6-(2-(6-[biotinyl]aminohexanoyl)aminoethyl)adeninedinucleotide,NAD

Purity:

≥95%byHPLC

SuppliedAs:

250µMaqueoussolution

Format:

Aqueousbuffersolution

Storage/StABIlity:

Stableatleast6monthsfromdateofreceipt,whenstoredasdirected

Application(s):

UsefulforthestudyofPARPenzymeactivityandDNAdamage,ortopurifyADP-ribosylatedenzymes.

Reference(s):

1.Bakondi,E.,etal.JHistochemCytochemJanuary2002vol.50no.191-98.
2.Zhang,J.(1997).Meth.Enzymol.280:255-65.
3.Till,S.,andLadurner,A.G.(2009).FrontBiosci.14:3246-3258.
4.Ying,W.(2007).FrontBiosci.12:1863-88.
5.Ying,W.(2008).Antioxidants&RedoxSignaling.10(2):179-206.

ApplicationReference(s):
1.Structure-functionanalysesofapertussis-liketoxinfrompathogenicEscherichiacolirevealadistinctmechanismofinhibitionoftrimericG-proteins(2017)
2. NovelPARP1/2inhibitormefuparibhydrochlorideelicitspotentinvitroandinvivoanticanceractivity,characteristicofhightissuedistribution(2017)
2. Activity-basedassayforhumanmono-ADP-ribosyltransferasesARTD7/PARP15andARTD10/PARP10aimedatscreeningandprofilinginhibitors(2013)

Warning(s):

Avoidfreeze/thawcycles

ScientificCategory:

PARP

ProductType:

Substrate

Datashownislot-specific.Contactusforspecificinformationonotherlots.

品牌介绍

bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。

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