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Bpsbioscience/Anti–RbAp 46/48 monoclonal antibody/25311/50 µg
Bpsbioscience/Anti–RbAp 46/48 monoclonal antibody/25311/50 µg
商品编号:
25311
品牌:
bpsbioscience
市场价:
¥5800.00
美元价:
3480.00
产品分类:
单克隆抗体
公司分类:
monoclonal_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
HostSpecies:Mouse
Clonality:monoclonal
Isotype:IgG2b
Background:
RbAp48(UniProtKB/Swiss–ProtentryQ09028)isacomponentofseveralcomplexeswhichregulatechromatinmetabolism.Theseinclude(1)thechromatinassemblyfactor1(CAF–1)complex,whichisrequiredforchromatinassemblyfollowingDNAreplicationandDNArepair;(2)thecorehistonedeacetylase(HDAC)complex,whichpromoteshistonedeacetylationandconsequenttranscriptionalrepression;(3)thenucleosomeremodellingandhistonedeacetylasecomplex(theNuRDcomplex),whichpromotestranscriptionalrepressionbyhistonedeacetylationandnucleosomeremodeling;(4)thePRC2/EED–EZH2complex,whichpromotesrepressionofhomeoticgenesduringdevelopment;and(5)theNURF(nucleosomeremodelingfactor)complex.ThereforeitmaytargetchromatinassemblyfactorsaswellaschromatinremodelingfactorsandhistonedeacetylasestotheirhistonesubstratesinanucleosomalDNAdependentmanner.
Description:
MonoclonalantibodyraisedinmouseagainstthefulllengthhumanRbAp48protein(Retinoblastoma–bindingproteinp48)fusedtoGST.TheantibodyrecognizesbothRbAp48andRbAp46.
Synonym(s):
RBBP7/4,RBBP–7/4,RBAP46/48,NURF55
AssayConditions:
WesternblotanalysisusingthemonoclonalantibodydirectedagainsthRbAp46/48
WesternblotwasperformedusingnuclearextractsfromHeLacells(HeLaNE,20μg)andthemonoclonalantibodyagainsthRbAp46/48(cat.#25311)diluted1:1,000inTBS-Tweencontaining5%skimmedmilk.ThemolecularweightMarker(inkDa)isshownontheleft),thepositionoftheproteinofinterestisshownontheright.
Concentration:
50µg/25µl
Formulation:
PBScontaining0.05%azideand0.05%ProClin300.
SpeciesReactivity:
Human
Purification:
ProteinGpurified
Immunogen:
recombinantprotein
Format:
Aqueousbuffersolution
Storage/StABIlity:
Storeat–80°Cforupto2years.Centrifugeafterfirstthawtomaximizeproductrecovery.Aliquottoavoidrepeatedfreeze/thawcycles.Aliquotsmaybestoredat–20°Cforatleastonemonth.
Application(s):
WB(1:1000)
Notes:
Theoptimalantibodyconcentrationshouldbedeterminedbytheend–user.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Antibodies
ProductType:
Antibody
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。