Bpsbioscience/Z-VEID-FMK/27669-1/5 mg
商品编号：
27669-1
品牌：
bpsbioscience
市场价：
¥7600.00
美元价：
4560.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:652.7Da
Formula:C31H45FN4O10
Target:Caspase6
Background:
VEIDisthespecificrecognitionsequenceforcaspase-6/Mch2.Caspase6isonlyoneofatleastthreeeffectorcaspases,theothersbeingcaspase3and7,thatareactiveduringcaspasedependentapoptosisLossofDNA-bindingactivityandTNFα-inducedapoptosiscanbepreventedbyZ-VEID-FMK.Thecaspase-6-speci?cinhibitorZ-VEID-FMKsigni?cantlypreventedapoptosisofcaspase-6-microinjectedneurons,andwasalsoabletoabolishthecleavageofprocaspase-8,althoughcaspase-6isactivateddownstreamofcaspase-8inFas-mediatedapoptosis.
Synonym(s):
Caspase-6inhibitor(fluoromethylketone);Benzyloxycarbonyl-Val-Glu(OMe)-Ile-?Asp(OMe)-fluoromethylketone
Purity:
≥90%byHPLC
BIOLOGicalActivity:
Werecommendusing2-10µMforinhibitingcaspaseactivityincellculture.Theoptimaldosemayvaryfordifferentcellsandcultureconditions.
Solubility:
SolubleinDMSO(20mM)
Storage/Stability:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Notes:
Theinhibitorisdesignedasamethylestertofacilitatecellpermeability.Iftheintendeduseisonpurifiedorrecombinantenzymes,esteraseshouldbeaddedtogeneratefreecarboxylgroups.
AminoAcidSequence:
Z-Val-Glu(OMe)-Ile-Asp(OMe)-CH?F
ScientificCategory:
ApoptosisInhibitor
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
