Bpsbioscience/Z-DQMD-FMK/27666-2/10 mg
商品编号：
27666-2
品牌：
bpsbioscience
市场价：
¥6500.00
美元价：
3900.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:685.7Da
Formula:C29H40FN5O11S
Target:Caspase3
Background:
Z-DQMD-FMKisapotentcell-permeableinhibitorofcaspase-3.Researchershaveshownthatexpressionofashortpeptideof15aminoacids,includingDQMDleadstoabrogationoftheapoptoticcascade,andtreatmentofcells,expressingtheDQMDpeptidewithtwoapoptosisinducers,etoposideandsodiumnitroprussideblockscelldeathbyapoptosis.StableexpressionoftheDQMDpeptideleadstoprotectionofcells,followinginductionofapoptosisandtotheoutgrowthandenrichmentofresistantcellcolonies.
Description:
Z-DQMD-FMKisasyntheticpeptidethatirreversIBLyinhibitstheactivityofCaspase-3.InhibitsMG132-inducedsmallcelllungcancercelldeathinvitro.Z-DQMD-FMKcanbeusedforbothinvitroandinvivostudies--seenoteforusingthisproductinvitro.
Synonym(s):
Z-DQMD-FMK;Benzyloxycarbonyl-Asp(OMe)-Gln-Met-?Asp(OMe)-fluoromethylketone
Purity:
≥88%byHPLC
BIOLOGicalActivity:
Werecommendusing2-10µMforinhibitingcaspaseactivityincellculture.Theoptimaldosemayvaryfordifferentcellsandcultureconditions.
Solubility:
SolubleinDMSO
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Notes:
Theinhibitorisdesignedasamethylestertofacilitatecellpermeability.Iftheintendeduseisonpurifiedorrecombinantenzymes,esteraseshouldbeaddedtogeneratefreecarboxylgroups.
AminoAcidSequence:
Z-Asp(OMe)-Gln-Met-Asp(OMe)-CH?F
ScientificCategory:
ApoptosisInhibitor
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
