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当前位置: 首页 > 产品中心 > cytokine > Bpsbioscience/Sepantronium溴化/27045/5 mg
商品详细Bpsbioscience/Sepantronium溴化/27045/5 mg
Bpsbioscience/Sepantronium溴化/27045/5 mg
Bpsbioscience/Sepantronium溴化/27045/5 mg
商品编号: 27045
品牌: bpsbioscience
市场价: ¥1240.00
美元价: 744.00
产地: 美国(厂家直采)
公司:
产品分类: 细胞因子
公司分类: cytokine
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MW:443.3Da
CASRegistry#:781661-94-7
Formula:C20H19BrN4O3
Description:
Sepantroniumbromide,alsoknownasYM155,isanovelsmallmoleculeinhibitorofexpressionoftheapoptosisinhibitingprotien,survivin.SepantroniumbromideinhibitedthethegrowthofvarioushumancancercelllinesinvitrowithGI50valuesinthelownMrange.Sepantroniumbromideblockedthegrowthof119humancancercelllines,withthegreatestinhibitioninlinesderivedfromnon-Hodgkin"slymphoma,hormone-refractoryprostatecancer,ovariancancer,sarcoma,non-small-celllungcancer,breastcancer,leukemiaandmelanoma,withanaverageGI50of15nM.Sepantroniumbromideinhibitedthegrowthoftumorcelllinesregardlessoftheirp53statusanddemonstratedsignificantantitumoractivityin5micexenograftmodels.Italsocausedtumorregressionsinvivo,possIBLybyitseffectsinreducingintratumoralsurvivinexpressionlevelsandincreasingapoptosis.
Synonym(s):
YM155
Purity:

≥98%

Solubility:
SolubleinDMSO
Format:
Acrystallinesolid.
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Nakahara,T.,etal.CancerRes.67:8014-8021(2007).
2.Nakahara,T.,etal.CancerSci.102:614-621(2011).
ScientificCategory:
Apoptosis
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。