Bpsbioscience/Cycloheximide/27746/1 g
商品编号:
27746
品牌:
bpsbioscience
市场价:
¥3700.00
美元价:
2220.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
MW:281.4Da
CASRegistry#:66-81-9
Formula:C15H23NO4
Background:
Cycloheximidehasbeenreportedtoinhibitboththesynthesisofproteinsandmacromolecules,aswellasaffectapoptosisineukaryotes.InhibitionofproteinsynthesisisbelievedtobemediatedthroughDNAtranslationarrest,asdemonstratedinratthymocytes.AlthoughCycloheximidehasbeenreportedtoinduceapoptosisinvariouscells,ithasalsobeenshowntoinhibitordelayinducedapoptosis.TheseobservationssuggestthatCycloheximide"seffectonapoptosismaynotbesolelythroughproteintranslationarrestandthatothermechanismsmaybeinvolved.CycloheximidehasalsobeenreportedtoinhibitFKBP12(peptidylprolylisomerasehFKBP12,PPIasehFKBP12)viacompetitiveinhibition.
Synonym(s):
NaramycinA;Actidione;3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide
Solubility:
Solubleinwater
Storage/StABIlity:
Storeatorbelow+4°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.
Application(s):
Cycloheximidecanbeusedtoinhibitproteinsynthesisorasanexperimentaltooltodeterminethehalf-lifeofaprotein.
Reference(s):
1.Christner,C.,etal.1999.J.Med.Chem.42,3615.
2.Lu,Q.,etal.1996.Arch.Biochem.Biophys.334,175.
3.Chow,S.C.,etal.1995.Exp.CellRes.216,149.
4.Cotter,T.G.,etal.1992.AnticancerRes.12,773.
2.Lu,Q.,etal.1996.Arch.Biochem.Biophys.334,175.
3.Chow,S.C.,etal.1995.Exp.CellRes.216,149.
4.Cotter,T.G.,etal.1992.AnticancerRes.12,773.
Warning(s):
Hygroscopic.Protectfrommoisture.Rapidlydestroyedinalkalinesolutions.
ScientificCategory:
ApoptosisInducers
ProductType:
Activator/Inducer
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。