Bpsbioscience/RbAp48, His-tag/50297/50 µg
商品编号：
50297
品牌：
bpsbioscience
市场价：
¥9000.00
美元价：
5400.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:Sf9insectcells
MW:48kDa
Genbank#:NM_005610
Tag(s):N-terminalHis-tag
a.a:2–end
Background:
RbAp48ispresentinproteincomplexesinvolvedinhistoneacetylationandchromatinassembly.Itispartofthechromatinassemblyfactor1(CAF-1)complex,whichisrequiredforchromatinassemblyfollowingDNAreplicationandDNArepair;thecorehistonedeacetylase(HDAC)complex,whichpromoteshistonedeacetylationandconsequenttranscriptionalrepression;thenucleosomeremodelingandhistonedeacetylasecomplex(theNuRDcomplex),whichpromotestranscriptionalrepressionbyhistonedeacetylationandnucleosomeremodeling;thePRC2/EED-EZH2complex,whichpromotesrepressionofhomeoticgenesduringdevelopment;theNURF(nucleosomeremodelingfactor)complex;andtheMi-2complexwhichhasbeenimplicatedinchromatinremodelingandtranscriptionalrepressionassociatedwithhistonedeacetylation.ThisproteinalsoseemstobeinvolvedintranscriptionalrepressionofE2F-responsivegenes.
Description:
HumanRbAp48(GenBankAccessionNo.NM_005610),a.a.2-endwithN-terminalHis-tag,MW=48kDa,expressedinabaculovirusexpressionsystem.
UniProt
Q09028
Synonym(s):
RBAP48,RetinoblastomaBindingProtein4,NURF55,ChromatinAssemblyFactor1SubunitC,CAF1p48,RBBP-4,Retinoblastoma-BindingProteinP48
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,3mMDTT,20%glycerol,and200mMimidazole
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C
Application(s):
Usefulforbindingstudiestoinvestigateprotein-proteininteractionsintheEZH2complex.AlsosuitableasanimmunogenorasastandardforWesternblotting.
Reference(s):
1.Varambally,S.etal.Science322(5908),1695-1699(2008).
2.Rakotobe,D.etal.,Virol.J.5,32(2008).
2.Rakotobe,D.etal.,Virol.J.5,32(2008).
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Miscellaneous
ProductType:
RecombinantProtein
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品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
