Bpsbioscience/ML161/27764-2/50毫克
商品编号：
27764-2
品牌：
bpsbioscience
市场价：
¥8100.00
美元价：
4860.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW: 361.2 Da
CAS Registry #: 423735-93-7
Formula: C17H17BrN2O2
Target: PAR-1
Background:
ML-161 is thought to act allosterically. ML-161 inhibits thrombin-induced platelet activation.
Description:
Allosteric and reversible inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 µM for the inhibition of platelet P-selectin expression on human platelets).
Synonym(s):
2-bromo-N-[3-(butanoylamino)phenyl]benzamide
Biological Activity:
ML-161 is an antagonist of the protease-activated receptor 1 (PAR1), that inhibits thrombin and SFLLN-induced platelet activation. ML-161 dose dependently inhibits SFLLN-induced expression of P-selectin with an IC50 of 0.26 µM.
Solubility:
Soluble in DMSO
Storage / Stability:
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s):
Dockendorff, C., et al. 2012. ACS Med. Chem. Lett. 3: 232-237
Scientific Category:
Other inhibitors
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
