Bpsbioscience/FKBP12, His-tag/40550/200 µg
商品编号：
40550
品牌：
bpsbioscience
市场价：
¥8300.00
美元价：
4980.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:13.1kDa
Genbank#:NM_054014
Tag(s):N-terminalHis-tag
a.a:fulllength
Background:
PPIasesacceleratethefoldingofproteins.Itcatalyzesthecis-transisomerizationofprolineimidicpeptidebondsinoligopeptidesKeepsinaninactiveconformationTGFBR1,theTGF-betatypeIserine/threoninekinasereceptor,preventingTGF-betareceptoractivationinabsenceofligand.RecruitesSMAD7toACVR1BwhichpreventstheassociationofSMAD2andSMAD3withtheactivinreceptorcomplex,therebyblockingtheactivinsignal.MaymodulatetheRYR1calciumchannelactivity.
Description:
HumanFKBP12(FK506bindingprotein1A,transcriptvariant12A),GenBankAccessionNo.NM_054014,fulllengthwithN-terminalHis-tag,MW=13.1kDa,expressedinanE.coliexpressionsystem.5References:1.Knappe,T.A.etal.,J.Mol.Biol.368(5),1458-1468(2007).2.Wear,M.A.etal.,ProteinExpr.Purif.51(1),80-95(2007).
Synonym(s):
FK506BindingProtein1,FKBP,Rotamase,ImmunophilinFKBP12,PPIase,CalstABIn
Formulation:
50mMTris-HCl,pH7.5,150mMNaCl,0.25mMDTT,0.1EGTA,0.1mMEDTA,0.1mMPMSF,50%glycerol.
Format:
Aqueousbuffersolution
Application(s):
UsefulfortestingrapamycininhibitionofmTOR.
Reference(s):
1.Knappe,T.A.etal.,J.Mol.Biol.368(5),1458-1468(2007).
2.Wear,M.A.etal.,ProteinExpr.Purif.51(1),80-95(2007).
ApplicationReference:
Structureofglutaraldehydecross-linkedryanodinereceptor(2013)
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Miscellaneous
ProductType:
RecombinantProtein
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品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
