4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:激酶、磷酸二酯酶、磷酸酶、组蛋白去甲基化酶、组蛋白甲基化转移酶、HDACs、聚ADP核糖聚合酶
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Routine_cell_strain > Bpsbioscience/CD27 CHO-K1稳定重组细胞系/60624/2小瓶
商品详细Bpsbioscience/CD27 CHO-K1稳定重组细胞系/60624/2小瓶
Bpsbioscience/CD27 CHO-K1稳定重组细胞系/60624/2小瓶
Bpsbioscience/CD27 CHO-K1稳定重组细胞系/60624/2小瓶
商品编号: 60624
品牌: bpsbioscience
市场价: ¥84500.00
美元价: 50700.00
产地: 美国(厂家直采)
公司:
产品分类: 常规细胞株
公司分类: Routine_cell_strain
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Background:
CD27isamemberofthetumornecrosisfactor(TNF)receptorsuperfamily,whichincludestheTcellco-stimulatoryreceptorsOX40,4-1BBandherpesvirusentrymediator(HVEM).CD27isexpressedonvarioustypesofTcells,Bcellsandasubsetofnaturalkillercells.ItactivatesNF-BandMAPK/JNKsignalinguponinteractionwithitsTNF-likeligand,CD70,whichisexpressedbynumeroustumorcells.AdaptorproteinsTRAF2andTRAF5canalsostimulateCD27signaling.ActivationofCD27leadstolymphoidproliferation,differentiation,apoptosis,andtheinductionoflong-termmemory.TheCD27/CD70pathwayisakeytargetforthedevelopmentoftreatmentsforcancerandinflammatorydiseases.
Description:

CHO-K1celllineexpressingfulllengthhumanCD27(TNFRSF7).ExpressionisconfirmedbyrealtimeqPCR,Westernblot,andflowcytometry.

ScreeningforantibodiesrecognizingCD27andscreeningantibodiesforbindingaffinities.Since
CHO-K1cellsdonotexpressendogenousCD27,thiscelllineservesasanexcellentmodelfor
studyingchangesinCD27-mediatedsignalingpathways,suchasNF-B,MAPKand
SAPK/JNK.

Synonym(s):
CD70antigen,TumorNecrosisFactorLigandSuperfamilyMember7,TNFSF7,CD27Ligand,Ki-24antigen,CD27-L,CD27LG,
SuppliedAs:
Eachvialcontains~2X106cellsin1mlof10%DMSO.
HostCellline:
CHO-K1
MycoplasmaTesting:
ThiscelllinehasbeenscreenedusingtheMycoAlert™MycoplasmaDetectionKit(Lonza,Cat.#LT07-118)toconfirmtheabsenceofMycoplasmacontamination.MycoAlertAssayControlSet(Lonza,Cat.#LT07-518)wasusedasapositivecontrol.
Format:
AqueoussolutioncontainingDMSO
Instructionsforuse:
Seedatasheet
Storage/StABIlity:
Storeinliquidnitrogenimmediatelyuponreceipt.
Reference(s):
1.AkibaHet.al.(1998)CD27,amemberofthetumornecrosisfactorreceptorsuperfamily,activatesNF-Bandstress-activatedproteinkinase/c-JunN-terminalkinaseviaTRAF2,TRAF5,andNF-Binducingkinase.J.Biol.Chem.273:13353
2.YamamotoHet.al.(1998)NF-BactivationinCD27signaling:InvolvementofTNFreceptor-associatedfactorinitssignalingandidentificationoffunctionalregionofCD27.J.Immunology161:4753-4759
Notes:

Contactusforpricing.

LicenseDisclosure:Purchaseofthiscelllinegrantsyouwitha10-yearlicensetousethiscelllineinyourimmediatelaboratory,forresearchuseonly.Thislicensedoesnotpermityoutoshare,distribute,sell,sublicense,orotherwisemakethecelllineavailableforusetootherlaboratories,departments,researchinstitutions,hospitals,universities,orbiotechcompanies.Thelicensedoesnotpermituseofthiscelllineinhumansorfortherapeuticordruguse.Thelicensedoesnotpermitmodificationofthecelllineinanyway.InappropriateuseordistributionofthiscelllinewillresultinrevocationofthelicenseandresultinanimmediateceaseofsalesanddistributionofBPSproductstoyourlaboratory.BPSdoesnotwarrantthesuitabilityofthecelllineforanyparticularuse,anddoesnotacceptanyliabilityinconnectionwiththehandlingoruseofthecellline.Modificationsofthiscellline,transfertoanotherfacility,orcommercialuseofthecellsmayrequireaseparatelicenseandadditionalfees;contactsales@bpSBIoscience.comfordetails.PublicationsusingthiscelllineshouldreferenceBPSBioscience,Inc.,SanDiego.

ScientificCategory:
Immunotherapy/CellSurfaceReceptor
ProductType:
CellLine
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。