Bpsbioscience/B-Raf（V600E）激酶分析试剂盒/48688/96反应
商品编号：
48688
品牌：
bpsbioscience
市场价：
¥9900.00
美元价：
5940.00
产品分类：
其它检测试剂盒
公司分类：
Other_kits
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Description:
B-raf,afterstimulationbyactivatedRAS,phosphorylatesMEK1resultinginactivationofthemitogen-activatedprotein(MAP)kinasecascade.SincetheMAPKcascadehasbeenshowntobeacriticalfactorinmelanomadevelopment,ithasbeenproposedthattargetingB-rafcouldbeapromisingapproachtocombatmelanoma.Moreimportantly,40-60%ofmelanomasdisplayamutationinBRAF,e.g.B-Raf(V600E),whichleadstoconstitutiveactivationoftheMAPkinasepathway.TheB-Raf(V600E)KinaseAssayKitisdesignedtomeasureB-Raf(V600E)kinaseactivityforscreeningandprofilingapplicationsusingKinase-Glo®MAXasadetectionreagent.Inaddition,theB-Raf(V600E)KinaseAssayKitincludeswildtypeB-RafenzymeasapositivecontrolforresearchersinvestigatingB-Raf(V600E)specificinhibitors.
Synonym(s):
BRAF1,RAFB1,B-raf1,MGC126806,MGC138284,BRAF(V600E)
SuppliedAs:
TheB-Raf(V600E)KinaseAssayKitcomesinaconvenient96-wellformat,withenoughpurifiedrecombinantB-Rafenzyme,B-Rafsubstrate,ATPandkinaseassaybufferfor100enzymereactions.
Format:
Instructionsforuse:
Seeassaykitdatasheetfordetailedprotocol.
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.
Application(s):
UsefulforstudyingenzymekineticsandscreeningsmallmolecularinhibitorsfordrugdiscoveryandHTSapplications.
Reference(s):
Cantwell-Dorris,ER,etal.MolCancerTher.2011Mar;10(3):385-94
ObaidNM,etal.IntJMolSci.2017Mar8;18(3).pii:E585.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Kinase
ProductType:
AssayKit
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
