Bpsbioscience/Den1, GST-tag/81084/25 µg
商品编号：
81084
品牌：
bpsbioscience
市场价：
¥4100.00
美元价：
2460.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species: Human
Host Species: E. coli
MW: 51 kDa
Tag(s): GST-tag
Background:
DEN1 (SENP8, NEDP1) is a deNEDDylase that deconjugates NEDD8 conjugates. A recent study demonstrated that DEN1 deNEDDylated the tumor suppressor breast cancer-associated protein BCA3. Full length DEN1 cleaves NEDD8-PLA2 with high efficiency.
Description:
Human Den1 recombinant protein, with GST-tag, expressed in E. coli.
UniProt
Q96LD8
Synonym(s):
DEN1, Deneddylase-1, FKSG8, HsT17512, NEDD8-specific protease 1, NEDP1, Protease, cysteine 2, PRSC2, Sentrin/SUMO-specific protease SENP8, Sentrin-specific protease 8
Format:
Aqueous buffer solution
Storage / Stability:
Store at or below –80°C. Stable as supplied for up to 1 year when stored dessicated at –80°C.
Application(s):
This enzyme is active in the NEDD8-IsoPro assay. Suggested Substrate: NEDD8-AMC
Reference(s):
1. Mendoza, H.M., et al., NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins. J. Biol. Chem., 2003. 278(28):25637?43.
2. Gan?Erdene, T., et al., Identification and characterization of DEN1, a deneddylase of the ULP family. J. Biol. Chem., 2003. 278(31):.28892?900.
3. Wu, K., et al., DEN1 Is a Dual Function Protease Capable of Processing the C-Terminus of Nedd8 and Deconjugating Hyper?neddylated CUL1. J. Biol. Chem., 2003. 278(31):28882?28891.
2. Gan?Erdene, T., et al., Identification and characterization of DEN1, a deneddylase of the ULP family. J. Biol. Chem., 2003. 278(31):.28892?900.
3. Wu, K., et al., DEN1 Is a Dual Function Protease Capable of Processing the C-Terminus of Nedd8 and Deconjugating Hyper?neddylated CUL1. J. Biol. Chem., 2003. 278(31):28882?28891.
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Ubiquitination (DeNEDDylase)
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
