Bpsbioscience/DBeQ/27703-1/10 mg
商品编号：
27703-1
品牌：
bpsbioscience
市场价：
¥3100.00
美元价：
1860.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW: 340.4 Da
CAS Registry #: 177355-84-9
Formula: C22H20N4
Description:
DBeQ is cell permeable, potent, selective and reversible inhibitor of the AAA-ATPase p97 (ATPase associated with diverse cellular activities). Ki=3.2 μM. DBeQ blocks both ubiquitin dependent and endoplasmic reticulum-associated degradation pathways, protein clearance pathways, and activates caspases -3 and -7 inducing apoptosis.
Synonym(s):
JRF 12; DBeQ; N2,N4–Dibenzylquinazoline–2,4–diamine
Purity:
>98% by TLC.
Solubility:
Soluble in DMSO (25 mg/ml)
Format:
Yellow powder
Storage / Stability:
Store at +4°C. Stable as supplied for up to 2 years when stored dessicated at +4°C. Store solutions at -20°C for up to 2 months.
Application(s):
Useful for the study of the ubiquitin-dependent and endoplasmic reticulum-associated degradation pathway (p97 ATPase)
Reference(s):
1. Chou TF, et al. Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways. Proc. Natl. Acad. Sci. USA. 2011. Mar 22; 108:4834-9.
Warning(s):
Protect from moisture.
Scientific Category:
Ubiquitin Enzymes
Product Type:
Inhibitors/Activators
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
