Bpsbioscience/Clasto-lactacystin β-lactone/27224/50 µg
商品编号：
27224
品牌：
bpsbioscience
市场价：
¥2300.00
美元价：
1380.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:213.2Da
CASRegistry#:154226-60-5
Formula:C10H15NO4
Description:
Clasto-lactacystinβ-lactone,alsoknownasOmuralideandβ-Clastolactacystin,targetsubiquitins.Itisanactivemetaboliteoflactacystinwhichinducesdifferentiationandinhibitionofcellcycleprogressioninseveraltumorcelllines.TheinhibitorirreversIBLyalkylatessubunitXofthe20sproteasome.Inhibitionofproteasomepeptidaseactivityresultsintheaccumulationofvariousubiquitinatedproteinswhichnormallyundergorapiddegredation.Therefore,theeffectsarepleiotropicandlargelydependontheexpressionpatterofsignalingproteinswithinthetreatedcell.
Synonym(s):
Omuralide
Purity:
≥98%byHPLC
BIOLOGicalActivity:
Clasto-lactacystinβ-lactoneinhibitsubiquitinproteasomepathwaysincellculturewithanIC50valueof1µM.
Concentration:
2.18mMsolution(0.05%byweight)
Format:
Solutioninmethylacetate
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
1.Omura,S.,etal.,J.Antibotics1991;44:113-116.
2.Corey,E.J.,etal.,J.Am.Chem.Soc.1992;114:10677-10678.
3.Fenteany,G.,etal.,JBiol.Chem.1998;273(15):8545-8548.
2.Corey,E.J.,etal.,J.Am.Chem.Soc.1992;114:10677-10678.
3.Fenteany,G.,etal.,JBiol.Chem.1998;273(15):8545-8548.
ScientificCategory:
Ubiquitin
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
