Bpsbioscience/Celastrol/27702-2/50 mg
商品编号：
27702-2
品牌：
bpsbioscience
市场价：
¥8600.00
美元价：
5160.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MW:450.6Da
CASRegistry#:34157-83-0
Formula:C29H38O4
Description:
Celastrolisanaturallyoccurringtriterpenoidantioxidantcompoundwithanti-inflammatoryactivity.InhibitsNFkappaB(IC50=270nM).Itinducesheatshockresponseandcytoprotectioninvariouscells.Celastrolinhibits20Sproteasomechymotrypsin-likeactivity(IC50=2.5μM).Cellpermeable.
Synonym(s):
Tripterine
Purity:
>98%byTLC.
Solubility:
SolubleinDMSO(45mg/ml)orEthanol(30mg/ml)
Format:
Redpowder
Storage/StABIlity:
Storeat+4°C.Stableassuppliedforupto2yearswhenstoreddessicatedat+4°C.Storesolutionsat-20°Cforupto1month.
Application(s):
UsefulforinhibitionofNF-kappa-B-dependentpathwaysandinhibitionof20Sproteasomechymotrypsin-likeactivity.
Reference(s):
1.Sethi,G.,etal.Celastrol,anoveltriterpene,potentiatesTNF-inducedapoptosisandsuppressesinvasionoftumorcellsbyinhibitingNF-kappaB-regulatedgeneproductsandTAK1-mediatedNF-kappaBactivation.Blood,2007,109:2727.
2.Westerheide,S.D.etal.Celastrolsasinducersoftheheatshockresponseandcytoprotection.J.Biol.Chem.2004.279:56053.
3.Kiaei,M.,etal.Celastrolblocksneuronalcelldeathandextendslifeintransgenicmousemodelofamyotrophiclateralsclerosis.Neurodegener.Dis.2005,2:246.
2.Westerheide,S.D.etal.Celastrolsasinducersoftheheatshockresponseandcytoprotection.J.Biol.Chem.2004.279:56053.
3.Kiaei,M.,etal.Celastrolblocksneuronalcelldeathandextendslifeintransgenicmousemodelofamyotrophiclateralsclerosis.Neurodegener.Dis.2005,2:246.
Warning(s):
Protectfromlight.Protectfrommoisture.Avoidfreeze/thawcycles.
ScientificCategory:
UbiquitinEnzymes
ProductType:
Inhibitors/Activators
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
