
Bpsbioscience/b-AP15 (NSC-687852)/27701-1/5 mg
商品编号:
27701-1
品牌:
bpsbioscience
市场价:
¥3600.00
美元价:
2160.00
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
MW: 419.4 Da
CAS Registry #: 1009817-63-3
Formula: C22H17N3O6
Description:
Blocks 26S proteasome activity by inhibiting the ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) activities of the 19S regulatory subunit without affecting the catalytic activity of the 20S core subunit. b-AP15 displays several differences to bortezomib including insensitivity to over-expression of the anti-apoptotic mediator Bcl-2 and anti-tumor activity in four solid tumor models.
Synonym(s):
b–AP15, NSC–687852, 3,5–Bis[(4–nitrophenyl)methylene]–1?–(1–oxo–2–propene–1–yl)–4–piperidone
Purity:
≥98% by HPLC.
Solubility:
Soluble in DMSO (35 mg/ml)
Format:
Pale yellow powder
Application(s):
Suitable for validation studies of the deubiquitinating activities of the 19S regulatory particle as a drug target, as well as cell-based and in vitro characterization UCH-L5 or USP14 activity.
Warning(s):
Protect from moisture.
Scientific Category:
Ubiquitin Enzymes
Product Type:
Inhibitors/Activators
Data shown is lot-specific. Contact us for specific information on other lots.
品牌介绍
bpsbioscience简介:为生命科学研究提供ELISA试剂盒(仅供科研)、抗体和抗原(仅供科研)、流式抗体,使您的检测结果更稳定可靠,用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀,吸附性好,空白值低,孔底透明度高,代做ELISA实验等。