Bpsbioscience/AMSH，His标签/81080/25µg
商品编号：
81080
品牌：
bpsbioscience
市场价：
¥8200.00
美元价：
4920.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:49kDa
Tag(s):His-tag
a.a:fulllength
Background:
AMSH(AssociatedMoleculewiththeSH3-domainofSTAM)isaJAMMdomain-containingproteinthatregulatesreceptorendosomalsortingoftheepidermalgrowthfactorreceptor(EGFR).RecombinantAMSHfunctionsasadeubiquitylaseinvitroandablationofAMSHactivitybyincubationofcellswithAMSHsiRNAenhancesthedegradationofEGFR.AMSHmediatedcleavageofK63linkedubiquitinchainsisenhancedinthepresenceofitsbindingpartnerSTAM.
Description:
HumanAMSHrecombinantprotein,fulllength,withHis-tag,expressedinE.coli.
UniProt
Q96FJ0
Synonym(s):
AssociatedmoleculewiththeSH3domainofSTAM,STAMBP,MGC126516,MGC126518,STAM-bindingprotein
Format:
Aqueousbuffersolution
Storage/StABIlity:
Storeatorbelow–80°C.Stableassuppliedforupto1yearwhenstoreddessicatedat–80°C.
Application(s):
ThisenzymecleavesK63-linkedubiquitinchainsinvitro.SuggestedSubstrate:DiUbiquitinK63
Reference(s):
1.McCullough,J.,etal.AMSHisanendosome-associatedubiquitinisopeptidase.JCellBiol,2004.166(4):p.487-92.
2.McCullough,J.,etal.Activationoftheendosome-associatedubiquitinisopeptidaseAMSHbySTAM,acomponentofthemultivesicularbody-sortingmachinery.CurrBiol,2006.16(2):p.160-5.
2.McCullough,J.,etal.Activationoftheendosome-associatedubiquitinisopeptidaseAMSHbySTAM,acomponentofthemultivesicularbody-sortingmachinery.CurrBiol,2006.16(2):p.160-5.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Deubiquitinase
ProductType:
RecombinantProtein
Datashownislot-specific.Contactusforspecificinformationonotherlots.
品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
