Bpsbioscience/Caspase6，His标签/80113/50µg
商品编号：
80113
品牌：
bpsbioscience
市场价：
¥99999999.99
美元价：
99999999.99
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Species:Human
HostSpecies:E.coli
MW:seeDescription
Genbank#:NM_001226
Tag(s):C-terminalHis-tag
a.a:1–293(end)
Background:
Caspase-6isamemberofthecaspase(cysteineaspartateprotease)familyofproteins,andhasbeenshowntobeanexecutionerproteinofapoptosis.Recentevidenceshowsthatcaspase-6isinvolvedinneurodegenerativediseases,suchasHuntington’sandAlzheimer’s.
Description:
HumanCaspase6(CASP6),GenBankAccessionNo.NM_001226,fulllength,a.a.1-293(end),withC-terminalHis-tag,expressedinanE.colicellexpressionsystem.Pro-caspase-6isactivatedbyautocleavagetoyield20kDaand18kDaproteins(largesubunit)andan11kDasmallsubunit(His-tag)thatdimerizetoformtheactiveenzyme.
UniProt
P55212
Synonym(s):
Caspase-6,CASP6,Caspase6,Mch2
SpecificActivity:
≥1720pmol/min/µg
AssayConditions:
AssayedusingBPS"sHomogeneousCaspase-6AssayKit,Cat.#80703.50mMHEPES,pH7.2,50mMNaCl,10mMEDTA,0.1%Chaps,5%glycerol,10mMDTT,and20µMCaspase6substrate.Incubatefor30minutesatroomtemperature.Fluorescenceintensityismeasuredatexc380/em505nm.
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,320mMimidazole,0.01%Tween-20,and20%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat-80°C.
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Halawani,D.,etal.,JNeurosci.2010Apr28;30(17):6132-42.
2.LeBlanc,A.,etal.,JBiolChem.1999Aug13;274(33):23426-36.
2.LeBlanc,A.,etal.,JBiolChem.1999Aug13;274(33):23426-36.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Protease
ProductType:
RecombinantProtein
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品牌介绍
bpsbioscience简介：为生命科学研究提供ELISA试剂盒（仅供科研）、抗体和抗原（仅供科研）、流式抗体，使您的检测结果更稳定可靠，用心服务科研。我公司国内总代理,华东地区代理bpsbioscience 专业经营进口胎牛血清、细胞因子、ELISA试剂盒、细胞、抗体、生物试剂、耗材、培养基、一抗、二抗、其产品吸附均匀，吸附性好，空白值低，孔底透明度高，代做ELISA实验等。
